	US 12,117,462 B2
	Lung cancer detection kit or device, and detection method
Hiroko Sudo, Kamakura (JP); Hitoshi Nobumasa, Kamakura (JP); Satoko Kozono, Kamakura (JP); Satoshi Kondou, Kamakura (JP); Junpei Kawauchi, Kamakura (JP); Atsushi Ochiai, Kashiwa (JP); and Motohiro Kojima, Kashiwa (JP)
Assigned to TORAY INDUSTRIES, INC., Tokyo (JP); and NATIONAL CANCER CENTER, Tokyo (JP)
Filed by TORAY INDUSTRIES, INC., Tokyo (JP); and NATIONAL CANCER CENTER, Tokyo (JP)
Filed on Oct. 31, 2022, as Appl. No. 17/977,377.
Application 17/977,377 is a division of application No. 16/800,755, filed on Feb. 25, 2020, granted, now 11,519,927.
Application 16/800,755 is a division of application No. 15/319,695, granted, now 10,620,228, issued on Apr. 14, 2020, previously published as PCT/JP2015/067533, filed on Jun. 18, 2015.
Claims priority of application No. 2014-125561 (JP), filed on Jun. 18, 2014.
Prior Publication US 2023/0251281 A1, Aug. 10, 2023
Int. Cl. C12Q 1/68 (2018.01); C12M 1/00 (2006.01); C12N 15/09 (2006.01); C12P 19/34 (2006.01); G01N 37/00 (2006.01)

CPC G01N 37/00 (2013.01) [C12M 1/00 (2013.01); C12N 15/09 (2013.01); C12Q 1/68 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01)]

6 Claims

1. A method for detecting lung cancer in a human subject, comprising

measuring an expression level of hsa-miR-3162-5p in a blood, serum or plasma sample from the subject;

comparing the measured expression level of hsa-miR-3162-5p to a control expression level for a healthy subject;

detecting an increased level of hsa-miR-3162-5p in the sample from the subject as compared to the control expression level from the sample from the healthy subject;

wherein the increased level of hsa-miR-3162-5p indicates that the subject has lung cancer; and

wherein the method further comprises treating the subject for the lung cancer or performing a diagnostic procedure on the subject with the lung cancer:

wherein the treatment comprises surgery, radiotherapy, chemotherapy or a combination thereof; and

wherein the diagnostic procedure comprises chest X-ray examination or diagnostic imaging of the lung of the human subject.