US 12,116,569 B2
Vortex generator for agitation of fluids during sample preparation
Alex Hofai Lee, Fremont, CA (US); and Daniel Chu, Hercules, CA (US)
Assigned to Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US)
Filed by Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US)
Filed on Jun. 2, 2023, as Appl. No. 18/328,085.
Application 18/328,085 is a continuation of application No. 17/759,417, granted, now 11,680,258, previously published as PCT/US2021/070106, filed on Feb. 1, 2021.
Claims priority of provisional application 62/989,285, filed on Mar. 13, 2020.
Prior Publication US 2023/0313172 A1, Oct. 5, 2023
Int. Cl. B01F 31/441 (2022.01); B01F 31/44 (2022.01); B01F 33/452 (2022.01); B01F 33/81 (2022.01); B01F 101/23 (2022.01); B01L 3/00 (2006.01); B03C 1/01 (2006.01); B03C 1/28 (2006.01); C12N 15/10 (2006.01)
CPC C12N 15/1013 (2013.01) [B01F 31/441 (2022.01); B01F 31/449 (2022.01); B01F 33/452 (2022.01); B01F 33/813 (2022.01); B01L 3/5085 (2013.01); B03C 1/01 (2013.01); B03C 1/288 (2013.01); B01F 2101/23 (2022.01); B01L 2200/0647 (2013.01); B03C 2201/18 (2013.01); B03C 2201/26 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A vortex generator assembly for performing nucleic acid isolation, comprising:
a sample holder comprising a body member forming a channel extending from a first end to an opposite second end of the sample holder, the sample holder further comprising a first plurality of wells for holding at least a fluid extending in a downwardly direction from a floor of the channel, each well having an interior volume; and
a sample holder cover comprising a base member comprising a floor extending from a first end to an opposite end of the sample holder cover, a removable retention mechanism configured to securely retain the sample holder cover in the channel when the base member is inserted into the channel, and a second plurality of vibration rods extending in a downwardly direction from the floor of the base member into the interior volume of a corresponding one of the first plurality of wells when the base member is inserted into the channel.