US 12,116,361 B2
Oxazolidinone compounds, liposome compositions comprising oxazolidinone compounds and method of use thereof
Daryl C. Drummond, Lincoln, MA (US); Suresh K. Tipparaju, Arlington, MA (US); Charles O. Noble, San Francisco, CA (US); Alexander Koshkaryev, Newton, MA (US); and Dmitri B. Kirpotin, San Francisco, CA (US)
Assigned to Akagera Medicines, Inc., Boxford, MA (US)
Filed by Akagera Medicines, Inc., Boxford, MA (US)
Filed on Dec. 1, 2022, as Appl. No. 18/060,900.
Application 18/060,900 is a continuation of application No. 17/351,631, filed on Jun. 18, 2021, granted, now 11,555,033.
Claims priority of provisional application 63/040,810, filed on Jun. 18, 2020.
Prior Publication US 2023/0126415 A1, Apr. 27, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. C07D 413/14 (2006.01); A61K 9/127 (2006.01); A61K 47/02 (2006.01); A61K 47/24 (2006.01); A61K 47/26 (2006.01); A61K 47/28 (2006.01); C07D 413/10 (2006.01)
CPC C07D 413/14 (2013.01) [A61K 9/127 (2013.01); A61K 9/1271 (2013.01); A61K 9/1272 (2013.01); A61K 9/1277 (2013.01); A61K 9/1278 (2013.01); A61K 47/02 (2013.01); A61K 47/24 (2013.01); A61K 47/26 (2013.01); A61K 47/28 (2013.01); C07D 413/10 (2013.01)] 10 Claims
 
1. A composition for the preparation of an oxazolidinone of the chemical formula

OG Complex Work Unit Chemistry
wherein the composition comprises:
(a) a compound of formula:

OG Complex Work Unit Chemistry
wherein R1 is —(CH2)2N(Me)2, —(CH2)2NHBoc, (CH2)3N(Me)2, or —(CH2)3N(Et)2, and
(b) a compound of formula

OG Complex Work Unit Chemistry
wherein R is NHBoc.