US 12,116,274 B2
Method for preparing octacalcium phosphate and octacalcium phosphate prepared thereby
Suk Young Kim, Gyeongsangbuk-do (KR); and Joo Seong Kim, Gyeongsangbuk-do (KR)
Assigned to HUDENS BIO CO., LTD., Gwangju (KR)
Filed by HUDENS BIO CO., LTD., Gwangju (KR)
Filed on Dec. 21, 2022, as Appl. No. 18/085,712.
Application 18/085,712 is a division of application No. 16/757,502, previously published as PCT/KR2018/012437, filed on Oct. 19, 2018.
Claims priority of application No. 10-2017-0136721 (KR), filed on Oct. 20, 2017.
Prior Publication US 2023/0124295 A1, Apr. 20, 2023
Int. Cl. C01B 25/32 (2006.01)
CPC C01B 25/327 (2013.01) [C01P 2002/60 (2013.01); C01P 2002/72 (2013.01); C01P 2004/03 (2013.01)] 8 Claims
OG exemplary drawing
 
1. Octacalcium phosphate prepared by a process comprising:
preparing a calcium phosphate solution;
controlling an initial pH by controlling a pH of the calcium phosphate solution to a range from 5 to 6 using an acidic solution;
heating the calcium phosphate solution of which the initial pH is controlled to a temperature ranging from 60° C. to 90° C.;
adding a heterogeneous seed comprising at least one selected from among octacalcium phosphate and dicalcium phosphate dihydrate to the heated calcium phosphate solution;
after adding the heterogeneous seed, adjusting a terminal pH by controlling the pH of the heated calcium phosphate solution to which the heterogeneous seed is added to a range from 5 to 6.