CPC B01J 20/24 (2013.01) [A61L 15/28 (2013.01); A61L 15/60 (2013.01); B01J 20/28011 (2013.01); B01J 20/28016 (2013.01); B01J 20/3021 (2013.01); B01J 20/3071 (2013.01); B01J 20/3085 (2013.01); C08B 1/08 (2013.01); C08B 11/12 (2013.01); C08B 15/005 (2013.01); C08J 3/126 (2013.01); C08J 3/245 (2013.01); B01J 2220/44 (2013.01); B01J 2220/68 (2013.01); C08J 2301/28 (2013.01)] | 24 Claims |
1. A method for manufacturing carboxymethyl cellulose particles, comprising:
(1) a step of obtaining alkalized cellulose by reacting a cellulose raw material with an alkalizer;
(2) a step of obtaining carboxymethyl cellulose by reacting the alkalized cellulose with a carboxy methylating agent;
(3) a primary cross-linking step of obtaining a slurry-phase carboxymethyl cellulose cross-linked body by reacting the carboxymethyl cellulose with a core cross-linker;
(4) a step of washing and dehydrating after filtering the slurry-phase carboxymethyl cellulose cross-linked body;
(5) a secondary cross-linking step of obtaining carboxymethyl cellulose having a core-shell structure by reacting the carboxymethyl cellulose cross-linked body having undergone Step (4) with a surface cross-linker; and
(6) a step of obtaining carboxymethyl cellulose particles having a core-shell structure by drying and pulverizing the carboxymethyl cellulose having a core-shell structure.
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