US 12,115,356 B2
Device and method for the delivery of a thrombin activated fibrin sealant
Jan Swartjes, Tubingen (DE); Stefanie Votteler, Reutlingen (DE); Markus Storr, Filderstadt (DE); and Bernd Krause, Rangendingen (DE)
Assigned to GAMBRO LUNDIA AB, Lund (SE)
Appl. No. 17/433,624
Filed by GAMBRO LUNDIA AB, Lund (SE)
PCT Filed Mar. 6, 2020, PCT No. PCT/EP2020/055975
§ 371(c)(1), (2) Date Aug. 25, 2021,
PCT Pub. No. WO2020/178419, PCT Pub. Date Sep. 10, 2020.
Claims priority of application No. 19161051 (EP), filed on Mar. 6, 2019.
Prior Publication US 2022/0143320 A1, May 12, 2022
Int. Cl. A61M 5/31 (2006.01); A61L 24/00 (2006.01); A61L 24/04 (2006.01); A61M 5/19 (2006.01); A61M 5/315 (2006.01)
CPC A61M 5/3145 (2013.01) [A61L 24/0036 (2013.01); A61L 24/043 (2013.01); A61M 5/19 (2013.01); A61M 5/31505 (2013.01)] 23 Claims
OG exemplary drawing
 
1. A dispenser of a sealant for hemostasis, comprising:
a container configured to receive a fibrinogen solution, and
an activation compartment,
the activation compartment being situated downstream of the container and comprising a functionalized support to which a coagulation factor is electrostatically immobilized, wherein the functionalized support is a functionalized resin comprising particles with a mean size of 150 to 300 μm.