US 12,115,285 B2
Cylindrical member for implantation
Taisuke Kogawa, Otsu (JP); Masaki Fujita, Otsu (JP); Kazuhiro Tanahashi, Otsu (JP); Satoshi Yamada, Otsu (JP); Nobuaki Tanaka, Otsu (JP); and Hiroshi Tsuchikura, Otsu (JP)
Assigned to Toray Industries, Inc., Tokyo (JP)
Appl. No. 17/269,502
Filed by Toray Industries, Inc., Tokyo (JP)
PCT Filed Aug. 30, 2019, PCT No. PCT/JP2019/034060
§ 371(c)(1), (2) Date Feb. 18, 2021,
PCT Pub. No. WO2020/045611, PCT Pub. Date Mar. 5, 2020.
Claims priority of application No. 2018-163208 (JP), filed on Aug. 31, 2018.
Prior Publication US 2021/0322650 A1, Oct. 21, 2021
Int. Cl. A61L 27/58 (2006.01); A61L 27/18 (2006.01); A61L 27/34 (2006.01); A61L 27/50 (2006.01); A61L 31/10 (2006.01); A61L 31/14 (2006.01); C09D 167/04 (2006.01); C09D 171/02 (2006.01)
CPC A61L 27/58 (2013.01) [A61L 27/18 (2013.01); A61L 27/34 (2013.01); A61L 27/507 (2013.01); A61L 31/10 (2013.01); A61L 31/148 (2013.01); C09D 167/04 (2013.01); C09D 171/02 (2013.01)] 8 Claims
 
1. A cylindrical body for an implant, comprising:
a cylindrical substrate having an elongation rate in the longitudinal direction, as measured under a tensile load of 20 N, of from 5 to 100%; and
a block copolymer composed of a polyalkylene glycol block(s) and a polyhydroxyalkanoic acid block(s);
wherein the block copolymer coated on the cylindrical substrate, wherein said polyhydroxyalkanoic acid block comprises a residue selected from the group consisting of lactic acid, glycolic acid and caprolactone residues;
wherein the ratio of the total mass of the alkylene glycol residue(s) with respect to the total mass of said block copolymer is from 5 to 25%; and
said block copolymer has a Young's modulus as measured in the form of a film of 200 MPa or less;
wherein upon implantation, a patency rate of at least 80% is maintained.