US 12,115,207 B2
Treatment of inflammation
Andrei Gudkov, East Aurora, NY (US); Elimelech Nesher, Eli (IL); Albert Pinhasov, Etz Ephraim (IL); Igor Koman, Tel Aviv (IL); and Yekaterina Leonova, Buffalo, NY (US)
Assigned to Ariel Scientific Innovations Ltd., Ariel (IL); and Health Research, Inc., Buffalo, NY (US)
Filed by Ariel Scientific Innovations Ltd., Ariel (IL); and Health Research, Inc., Buffalo, NY (US)
Filed on Oct. 13, 2020, as Appl. No. 17/068,849.
Application 17/068,849 is a continuation of application No. PCT/IL2019/050417, filed on Apr. 12, 2019.
Prior Publication US 2021/0023164 A1, Jan. 28, 2021
Int. Cl. A61K 38/12 (2006.01); A61K 38/08 (2019.01); A61P 29/00 (2006.01)
CPC A61K 38/12 (2013.01) [A61K 38/08 (2013.01); A61P 29/00 (2018.01)] 1 Claim
 
1. A method of treating type I interferon-associated inflammation due to radiation in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a peptide consisting of cyclic SEQ ID NO: 4, thereby treating the inflammation due to radiation, wherein the N terminus of the peptide is bound to the C terminus of the peptide and wherein the N terminal amino acid and the C terminal amino acids are cysteines.