US 12,114,972 B2
Methods, systems, and devices for continuous glucose monitoring
Georgios Mallas, Los Angeles, CA (US); Andrea Varsavsky, Santa Monica, CA (US); Peter Ajemba, Canyon Country, CA (US); Jeffrey Nishida, Chicago, IL (US); Keith Nogueira, Mission Hills, CA (US); Elaine Gee, Windsor, CA (US); Leonardo Nava-Guerra, Alhambra, CA (US); Jing Liu, Woodland Hills, CA (US); Sadaf S. Seleh, Encino, CA (US); Taly G. Engel, Los Angeles, CA (US); Benyamin Grosman, Valley Village, CA (US); Steven Lai, Granada Hills, CA (US); Luis A. Torres, South Gate, CA (US); Chi A. Tran, Falcon Heights, MN (US); and David M. Sniecinski, Los Angeles, CA (US)
Assigned to MEDTRONIC MINIMED, INC., Northridge (CA)
Filed by MEDTRONIC MINIMED, INC., Northridge, CA (US)
Filed on Jan. 27, 2020, as Appl. No. 16/773,422.
Claims priority of provisional application 62/800,297, filed on Feb. 1, 2019.
Prior Publication US 2020/0245910 A1, Aug. 6, 2020
Int. Cl. A61B 5/145 (2006.01); A61B 5/1468 (2006.01)
CPC A61B 5/14532 (2013.01) [A61B 5/1468 (2013.01); A61B 2560/0223 (2013.01); A61B 2562/16 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A method of optimizing a sensor glucose (SG) calculation for a glucose sensor used for measuring the level of glucose in the body of a user, said glucose sensor including physical sensor electronics, a microcontroller, a counter electrode, and a working electrode, the method comprising:
(a) periodically measuring, by the physical sensor electronics, electrode current (Isig) signals for the working electrode;
(b) periodically performing, by the microcontroller, an Electrochemical Impedance Spectroscopy (EIS) procedure by causing an alternating current (AC) source to apply a periodic AC signal to the working electrode to generate EIS-related data for the working electrode;
(c) periodically measuring, by the physical sensor electronics, a potential difference between the counter electrode and the working electrode (Vcntr);
(d) periodically obtaining a blood glucose (BG) value for the user;
(e) determining in real-time, by said microcontroller, whether a calibration error exists;
(f) when there is no calibration error, calculating in real-time, by said microcontroller, a sensor glucose (SG) value based on said BG, Isig, Vcntr, and EIS-related data; and
(g) causing the microcontroller to communicate the calculated SG value to at least one of an insulin-administering device or a mobile communication device.