US 12,444,162 B2
Analysis tool for performing patient-specific analysis of flows through flexible tubular organs
John Erik Pandolfino, Wilmette, IL (US); Neelesh Ashok Patankar, Buffalo Grove, IL (US); Sourav Halder, Evanston, IL (US); Shashank Acharya, Evanston, IL (US); and Peter James Kahrilas, Chicago, IL (US)
Assigned to Northwestern University, Evanston, IL (US)
Appl. No. 17/779,124
Filed by Northwestern University, Evanston, IL (US)
PCT Filed Nov. 23, 2020, PCT No. PCT/US2020/061875
§ 371(c)(1), (2) Date May 23, 2022,
PCT Pub. No. WO2021/102436, PCT Pub. Date May 27, 2021.
Claims priority of provisional application 62/939,085, filed on Nov. 22, 2019.
Prior Publication US 2022/0405923 A1, Dec. 22, 2022
Int. Cl. G06V 10/44 (2022.01); G06T 3/40 (2006.01); G06T 7/00 (2017.01); G06T 7/11 (2017.01); G06T 7/20 (2017.01); G06V 10/82 (2022.01); G16H 15/00 (2018.01); G16H 30/40 (2018.01)
CPC G06V 10/454 (2022.01) [G06T 3/40 (2013.01); G06T 7/0012 (2013.01); G06T 7/11 (2017.01); G06T 7/20 (2013.01); G06V 10/82 (2022.01); G16H 15/00 (2018.01); G16H 30/40 (2018.01); G06T 2207/10064 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01); G06T 2207/30092 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A method for analyzing flow through a tubular organ of a subject, the method comprising:
(a) accessing medical image data acquired from the subject, the medical image data depicting transport of a bolus through a tubular organ of the subject;
(b) generating segmented medical image data by segmenting the medical image data in order to segment the bolus as it is transported through the tubular organ of the subject;
(c) generating flow analysis data by inputting the segmented medical image data to a reduced-order model, generating output as the flow analysis data, wherein the flow analysis data comprise at least one of fluid flow rate data, pressure field data, wall stiffness data, or relaxation data, each determined during bolus transport through the tubular organ of the subject.