| CPC G06T 15/08 (2013.01) [A61B 6/52 (2013.01); A61B 6/5205 (2013.01); A61B 6/582 (2013.01); A61B 34/20 (2016.02); G06T 7/33 (2017.01); G06T 7/73 (2017.01); G06T 11/006 (2013.01); A61B 2034/2065 (2016.02); A61B 2090/367 (2016.02); A61B 2090/376 (2016.02); A61B 2090/3966 (2016.02); G06T 2207/10116 (2013.01); G06T 2207/30204 (2013.01)] | 6 Claims |

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1. A method for constructing a three-dimensional (3D) volume from a set of two or more medical images, the method comprising:
A) acquiring two or more biplanar radiographic images with an X-ray imaging device;
B) calibrating each of the biplanar radiographic images both intrinsically and extrinsically in relation to a common coordinate system wherein the intrinsic calibration includes determining one of lens distortions and focal length of the X-ray imaging device;
C) encoding the calibrated images using a machine learning or deep learning algorithm executing on a processor;
D) back-projecting the encoded images into the common coordinate system based on known relative 3D poses; and
E) decoding the back-projected images to reconstruct the 3D volume.
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