US 12,443,564 B2
System and method for adaptive quality driven compression of genomic data using neural networks
Zhu Li, Overland Park, KS (US); Paras Maharjan, Kansas City, MO (US); and Brian Galvin, Silverdale, WA (US)
Assigned to ATOMBEAM TECHNOLOGIES INC., Moraga, CA (US)
Filed by AtomBeam Technologies Inc., Moraga, CA (US)
Filed on Feb. 7, 2025, as Appl. No. 19/048,846.
Application 19/048,846 is a continuation in part of application No. 18/769,416, filed on Jul. 11, 2024, granted, now 12,224,044.
Application 18/769,416 is a continuation in part of application No. 18/420,771, filed on Jan. 24, 2024, granted, now 12,095,484, issued on Sep. 17, 2024.
Application 18/420,771 is a continuation in part of application No. 18/410,980, filed on Jan. 11, 2024, granted, now 12,068,761, issued on Aug. 20, 2024.
Application 18/410,980 is a continuation in part of application No. 18/537,728, filed on Dec. 12, 2023, granted, now 12,058,333, issued on Aug. 6, 2024.
Prior Publication US 2025/0190400 A1, Jun. 12, 2025
This patent is subject to a terminal disclaimer.
Int. Cl. H03M 7/00 (2006.01); G06F 16/174 (2019.01)
CPC G06F 16/1744 (2019.01) 14 Claims
OG exemplary drawing
 
1. A system for recovering information lost during data compression, comprising:
a computing system comprising at least a memory and a processor;
a quality analysis engine configured to evaluate importance of genomic regions and assign quality scores;
a rate control engine configured to determine compression rates based on the quality scores;
a neural network configured to recover lost information from a plurality of correlated genomic datasets that have been compressed with lossy compression, wherein the neural network comprises:
a plurality of recurrent layers for feature extraction;
a channel-wise transformer with attention to capture inter-channel dependencies; and
a deblocking network composed of the recurrent layers and channel-wise transformer; and
a decoder configured to:
receive compressed data comprising the plurality of correlated genomic datasets;
decompress the compressed data; and
process the decompressed data using the neural network to recover information lost during lossy compression.