US 12,442,726 B2
Mask-based testing system for detecting biomarkers in exhaled breath condensate, aerosols and gases
John J. Daniels, Madison, CT (US)
Filed by John J. Daniels, Madison, CT (US)
Filed on Oct. 7, 2020, as Appl. No. 17/065,488.
Application 17/065,488 is a continuation in part of application No. 16/882,447, filed on May 23, 2020, granted, now 12,092,639.
Application 17/065,488 is a continuation in part of application No. 16/876,054, filed on May 17, 2020, granted, now 12,031,982.
Claims priority of provisional application 63/026,052, filed on May 17, 2020.
Claims priority of provisional application 63/019,378, filed on May 3, 2020.
Claims priority of provisional application 63/012,247, filed on Apr. 19, 2020.
Prior Publication US 2021/0325279 A1, Oct. 21, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 1/22 (2006.01); A61B 5/00 (2006.01); A61B 10/00 (2006.01); C01B 32/158 (2017.01); G01N 1/38 (2006.01); G01N 33/487 (2006.01)
CPC G01N 1/2226 (2013.01) [A61B 5/0002 (2013.01); A61B 5/6803 (2013.01); A61B 5/6898 (2013.01); A61B 10/00 (2013.01); C01B 32/158 (2017.08); G01N 1/38 (2013.01); G01N 33/487 (2013.01); A61B 2010/0087 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A testing system for detecting a biomarker received from lungs and airways of a test subject, comprising:
an exhaled breath condensate (EBC) collector integrated into an inside of a face mask worn by the test subject, the EBC collector for converting breath vapor received from the lungs and airways of the test subject into a fluid biosample, where the EBC collector comprises a droplet harvesting structure including a hydrophobic field for receiving the breath vapor and forming fluid droplets from the received breath vapor, and hydrophilic channels for receiving the fluid droplets from the hydrophobic field and channeling the fluid droplets together to form the fluid biosample;
a biosensor fixed to the face mask for receiving a fluid biosample from the EBC collector, testing the fluid biosample for a target biomarker,
and generating a test signal dependent on the target biomarker in the fluid biosample; and
an electronic circuit fixed to the face mask for receiving the test signal, determining from the test signal a test result signal depending on the target biomarker, and
transmitting the test result signal to a remote receiver.