US 12,442,632 B2
Optical diffraction tomography microscope
Sebastien Equis, Penthalaz (CH); Yann Cotte, Saint Saphorin sur Morges (CH); and Pierre-Alain Cotte, Amberg (DE)
Assigned to NANOLIVE SA, Tolochenaz (CH)
Appl. No. 18/257,527
Filed by NANOLIVE SA, Tolochenaz (CH)
PCT Filed Dec. 13, 2021, PCT No. PCT/EP2021/085565
§ 371(c)(1), (2) Date Jun. 14, 2023,
PCT Pub. No. WO2022/128966, PCT Pub. Date Jun. 23, 2022.
Claims priority of application No. 20213957 (EP), filed on Dec. 14, 2020.
Prior Publication US 2024/0044636 A1, Feb. 8, 2024
Int. Cl. G01B 9/02 (2022.01); G02B 21/06 (2006.01); G03H 1/00 (2006.01)
CPC G01B 9/02047 (2013.01) [G02B 21/06 (2013.01); G03H 1/0005 (2013.01); G03H 2001/005 (2013.01)] 56 Claims
OG exemplary drawing
 
1. An optical diffraction tomography microscope, comprising:
an illumination system; and
a wave collection system including a lens and a holographic detection system, wherein
the illumination system comprises a plurality of static sample illumination beam sources arranged around a sample observation zone of the illumination system within which a sample container is positionable,
the plurality of static sample illumination beam sources are configured to emit sample illumination beams at a beam inclination angle (β) with respect to a center axis (A) extending through the sample observation zone,
the plurality of static sample illumination beam sources are connected to a light generator configured to switch from one beam source to the next to generate a moving sample illumination beam around the sample observation zone, and
the holographic detection system is configured to capture a plurality of holograms generated by interference of said sample illumination beams with reference beams generated by the holographic detection system.