US 12,442,039 B2
Resin composition and flow cells incorporating the same
Timothy J. Merkel, San Diego, CA (US); Wayne N. George, London (GB); Andrew A. Brown, Cambridge (GB); Audrey Zak, San Diego, CA (US); Gianluca Andrea Artioli, Cambridge (GB); Julia Morrison, Grays (GB); Nikolai Romanov, Cambridge (GB); Lorenzo Berti, San Diego, CA (US); and Graham Boud, San Diego, CA (US)
Assigned to Illumina, Inc., San Diego, CA (US); and Illumina Cambridge Limited, Cambridge (GB)
Filed by ILLUMINA, INC., San Diego, CA (US); and ILLUMINA CAMBRIDGE LIMITED, Cambridge (GB)
Filed on Dec. 29, 2023, as Appl. No. 18/400,702.
Application 18/400,702 is a division of application No. 16/515,790, filed on Jul. 18, 2019, granted, now 11,884,976.
Claims priority of provisional application 62/701,228, filed on Jul. 20, 2018.
Prior Publication US 2024/0132954 A1, Apr. 25, 2024
Int. Cl. C12Q 1/6874 (2018.01); C08F 30/08 (2006.01); C08G 77/442 (2006.01); C08L 33/04 (2006.01); C08L 63/00 (2006.01); C09D 153/00 (2006.01); C09D 163/00 (2006.01); C12Q 1/6876 (2018.01)
CPC C12Q 1/6874 (2013.01) [C08F 30/08 (2013.01); C08G 77/442 (2013.01); C08L 33/04 (2013.01); C08L 63/00 (2013.01); C09D 153/00 (2013.01); C09D 163/00 (2013.01); C12Q 1/6876 (2013.01)] 5 Claims
 
1. A resin composition, consisting of:
a free radical curable resin matrix including an acrylate and a siloxane;
a free radical photoinitiator selected from the group consisting of 2,2-dimethoxy-2-phenylacetophenone, a blend of diphenyl(2,4,6-trimethylbenzoyl) phosphine oxide and 2-hydroxy-2-methylpropiophenone, phenylbis(2,4,6-trimethylbenzoyl) phosphine oxide, ethyl(2,4,6-trimethylbenzoyl)phenylphosphinate, and combinations thereof; and
a solvent;
wherein, when cured, the resin composition has low or no autofluorescence when exposed to blue excitation wavelengths ranging from about 380 nm to about 480 nm or green excitation wavelengths ranging from about 510 nm to about 560 nm, and
wherein the free radical curable resin matrix is an acryloxypropyl methylsiloxane homopolymer having a structure:

OG Complex Work Unit Chemistry
wherein m is 30 to 200.