US 12,442,029 B2
Method and system for imaging a blood sample
Joseph Joel Pollak, Neve Daniel (IL); Arnon Houri Yafin, Jerusalem (IL); and Seth J. Salpeter, Jerusalem (IL)
Assigned to S.D. Sight Diagnostics Ltd., Tel Aviv (IL)
Filed by S.D. Sight Diagnostics Ltd., Tel Aviv (IL)
Filed on Aug. 8, 2022, as Appl. No. 17/882,702.
Application 17/882,702 is a continuation of application No. 16/106,085, filed on Aug. 21, 2018, granted, now 11,434,515.
Application 16/106,085 is a continuation of application No. 15/083,610, filed on Mar. 29, 2016, granted, now 10,093,957, issued on Oct. 9, 2018.
Application 15/083,610 is a continuation of application No. 14/440,864, granted, now 9,329,129, issued on May 3, 2016, previously published as PCT/IL2014/050585, filed on Jun. 30, 2014.
Claims priority of application No. 227276 (IL), filed on Jul. 1, 2013.
Prior Publication US 2022/0390734 A1, Dec. 8, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 21/64 (2006.01); C12Q 1/04 (2006.01); G01N 1/28 (2006.01); G01N 1/38 (2006.01); G01N 15/1433 (2024.01); G01N 33/49 (2006.01); G02B 21/00 (2006.01); G02B 21/16 (2006.01); G02B 21/34 (2006.01); G02B 21/36 (2006.01); G01N 15/01 (2024.01)
CPC C12Q 1/04 (2013.01) [G01N 1/2813 (2013.01); G01N 1/38 (2013.01); G01N 15/1433 (2024.01); G01N 21/6428 (2013.01); G01N 21/6458 (2013.01); G01N 21/6486 (2013.01); G01N 33/49 (2013.01); G02B 21/0012 (2013.01); G02B 21/16 (2013.01); G02B 21/34 (2013.01); G02B 21/361 (2013.01); G02B 21/367 (2013.01); G01N 15/01 (2024.01); G01N 2021/6439 (2013.01)] 13 Claims
OG exemplary drawing
 
1. A method comprising:
using a carrier that is a closed cavity that includes an inlet into the closed cavity, a base surface, and a closed top;
introducing, using capillary forces, a cell suspension comprising red blood cells from outside the carrier into the closed cavity via the inlet;
allowing the cells, including the red blood cells, in the cell suspension to settle on the base surface of the carrier to form a monolayer of cells on the base surface of the carrier, such that after the cell suspension settles on the base surface, the density of the cells of the cell suspension is between about 10,000 and about 30,000 cells per mm2, and
acquiring at least one microscope image of at least a portion of the monolayer of cells.