	US 12,441,954 B2
	Powdery, musky odorant macrocycles
Anthony Alexander Birkbeck, Satigny (CH); and Umberto Maddalena, Satigny (CH)
Assigned to FIRMENICH SA, Satigny (CH)
Appl. No. 17/757,728
Filed by FIRMENICH SA, Satigny (CH)
PCT Filed Dec. 17, 2020, PCT No. PCT/EP2020/086703 § 371(c)(1), (2) Date Jun. 20, 2022, PCT Pub. No. WO2021/122945, PCT Pub. Date Jun. 24, 2021.
Claims priority of application No. 19218958 (EP), filed on Dec. 20, 2019.
Prior Publication US 2023/0031807 A1, Feb. 2, 2023
Int. Cl. C11B 9/00 (2006.01); C07D 313/00 (2006.01)

CPC C11B 9/0084 (2013.01) [C07D 313/00 (2013.01)]

16 Claims

1. A composition of matter comprising:

a) 0.5 to 85% w/w of (Z)-oxacyclohexadec-12-en-2-one;

b) 0.5 to 30% w/w of (E)-oxacyclohexadec-12-en-2-one;

c) 0 to 30% w/w of (E)-oxacyclohexadec-13-en-2-one; and

d) 0.5 to 85% w/w of (Z)-oxacyclohexadec-13-en-2-one,

the percentage being relative to the total weight of the composition of matter;

wherein the weight ratio of the E-diastereoisomers to the Z-diastereoisomers is comprised in the range between 40:60 and 15:85.