US 12,441,765 B2
Peptides and medical uses thereof
Menotti Ruvo, San Nicola alla Strada (IT); Davide Rosiello, Naples (IT); and Sandro De Falco, Naples (IT)
Assigned to ANBITION S.R.L., Naples (IT)
Appl. No. 17/275,023
Filed by Anbition S.R.L., Naples (IT)
PCT Filed Sep. 11, 2019, PCT No. PCT/IB2019/057636
§ 371(c)(1), (2) Date Mar. 10, 2021,
PCT Pub. No. WO2020/053772, PCT Pub. Date Mar. 19, 2020.
Claims priority of application No. 102018000008493 (IT), filed on Sep. 11, 2018.
Prior Publication US 2022/0064216 A1, Mar. 3, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 7/08 (2006.01); A61P 27/02 (2006.01); A61K 38/00 (2006.01)
CPC C07K 7/08 (2013.01) [A61P 27/02 (2018.01); A61K 38/00 (2013.01)] 8 Claims
 
1. An isolated peptide characterized by the following formula (II)

OG Complex Work Unit Chemistry
wherein
Glu indicates glutamic acid;
Cys(Bzl) indicates benzyl cysteine;
Cha indicates cyclohexylalanine;
Y2 is
an α-amino acid having at least one side chain comprising a thiol, or a thioether group
Z1 and Z2 indicate lysine.