US 12,441,704 B2
Compounds active towards nuclear receptors
Sanne Schrøder Glad, Copenhagen (DK); Ian Sarvary, Copenhagen (DK); Alex Haahr Gouliaev, Copenhagen (DK); Thomas Franch, Copenhagen (DK); Søren Jensby Nielsen, Copenhagen (DK); Luigi Piero Stasi, Copenhagen (DK); Montserrat Erra Solà, Sant Feliu de Llobregat (ES); Lorena Taboada Martínez, Sant Feliu de Llobregat (ES); Joan Taltavull Moll, Sant Feliu de Llobregat (ES); Juan Francisco Caturla Javaloyes, Sant Feliu de Llobregat (ES); and Lluís Miquel Pagès Santacana, Sant Feliu de Llobregat (ES)
Assigned to NUEVOLUTION A/S, Copenhagen (DK)
Filed by NUEVOLUTION A/S, Copenhagen (DK)
Filed on May 5, 2023, as Appl. No. 18/143,975.
Application 18/143,975 is a division of application No. 17/126,182, filed on Dec. 18, 2020, granted, now 11,685,727.
Claims priority of provisional application 63/064,502, filed on Aug. 12, 2020.
Claims priority of provisional application 62/951,221, filed on Dec. 20, 2019.
Prior Publication US 2023/0271937 A1, Aug. 31, 2023
Int. Cl. A61K 31/506 (2006.01); A61P 19/02 (2006.01); A61P 21/00 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 413/14 (2006.01)
CPC C07D 401/12 (2013.01) [A61P 19/02 (2018.01); A61P 21/00 (2018.01); C07D 401/14 (2013.01); C07D 413/14 (2013.01)] 18 Claims
 
1. A method of treating a disease selected from acne, atopic dermatitis, lichen planus, multiple sclerosis, rheumatoid arthritis, juvenile idiopathic arthritis, osteoarthritis, ankylosing spondylitis, psoriasis, psoriatic arthritis, ichthyoses, bullous diseases, hidradenitis suppurativa, ulcerative colitis, colitis, Crohn's disease, inflammatory bowel disease (IBD) and lupus erythematosus in a subject suffering therefrom, the method comprising: administering to the subject a compound, stereoisomer, or salt having a structure selected from the group consisting of:

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry