US 12,440,835 B2
Methods, systems and apparatus for separating components of a biological sample
Sanjay Batra, Doylestown, PA (US); Elizabeth G. Cellucci, Doylestown, PA (US); Justin Joseph Batra, Doylestown, PA (US); and Jaya Krishna Rose Batra, Doylestown, PA (US)
Assigned to Vias Partners, LLC
Appl. No. 17/424,871
Filed by VIAS PARTNERS LLC, Doylestown, PA (US)
PCT Filed Jan. 21, 2020, PCT No. PCT/US2020/014446
§ 371(c)(1), (2) Date Jul. 21, 2021,
PCT Pub. No. WO2020/154305, PCT Pub. Date Jul. 30, 2020.
Claims priority of provisional application 62/794,961, filed on Jan. 21, 2019.
Prior Publication US 2022/0088589 A1, Mar. 24, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. B01L 3/00 (2006.01); A61K 35/16 (2015.01); A61K 35/19 (2015.01); A61K 36/16 (2006.01); B01D 17/02 (2006.01); B04B 5/04 (2006.01); C12N 5/078 (2010.01)
CPC B01L 3/50215 (2013.01) [A61K 35/16 (2013.01); A61K 35/19 (2013.01); B01D 17/0217 (2013.01); B04B 5/0414 (2013.01); C12N 5/0644 (2013.01); B01L 2200/026 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/042 (2013.01); B01L 2300/046 (2013.01); B01L 2300/0832 (2013.01); B01L 2400/0409 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A method for:
increasing a number of platelets available for administration, in a post-centrifuged sample, to a patient, comprising:
centrifuging a collection tube containing a biological sample and a separation barrier; and
maintaining the collection tube at an angle of from about (−)15° to about 90°; and
agitating the collection tube at said angle and at a rate effective to create a thin layer of foam on top of said biological sample;
wherein the collection tube is agitated for at least five seconds; and
wherein the number of platelets available for administration to a patient is increased by at least 10% versus the number of platelets available for administration to a patient provided by a control system.