US 12,440,699 B2
Phototherapy device and phototherapy instrument used for irradiation of the head, and therapy method thereof
Liang Chen, Haining (CN); Xunbin Wei, Haining (CN); Qingqiang Meng, Haining (CN); Yuanzhen Suo, Haining (CN); Jing Yu, Haining (CN); Min Xie, Haining (CN); Bo Zhou, Haining (CN); Qiyuan Zhuang, Haining (CN); Lechan Tao, Haining (CN); and Yong Huang, Haining (CN)
Assigned to ZHEJIANG BRAINHEALTH MEDICAL TECHNOLOGY CO., LTD., Hangzhou (CN)
Appl. No. 17/620,403
Filed by ZHEJIANG BRAINHEALTH MEDICAL TECHNOLOGY CO., LTD., Hangzhou (CN)
PCT Filed Jun. 16, 2020, PCT No. PCT/CN2020/096249
§ 371(c)(1), (2) Date Dec. 17, 2021,
PCT Pub. No. WO2020/173512, PCT Pub. Date Sep. 3, 2020.
Claims priority of application No. 201910522271.6 (CN), filed on Jun. 17, 2019.
Prior Publication US 2022/0362576 A1, Nov. 17, 2022
Int. Cl. A61N 5/06 (2006.01)
CPC A61N 5/0618 (2013.01) [A61N 2005/0647 (2013.01); A61N 2005/0652 (2013.01); A61N 2005/0659 (2013.01)] 26 Claims
OG exemplary drawing
 
1. A method of treating Alzheimer's disease, the method comprising providing a helmet-type phototherapy device for head irradiation, the helmet-type phototherapy device, including:
a near-infrared irradiation module configured for emitting near-infrared light to the head, wherein the near-infrared irradiation module includes multiple light-emitting devices of near-infrared light-emitting diode and/or laser diode; and
a control component, coupled with the near-infrared irradiation module and configured for controlling operation of the near-infrared irradiation module, wherein the control component controls the near-infrared irradiation module to operate in a pulsed light irradiation mode;
applying a first near-infrared light having a central wavelength of 1020-1120 nm to the head of a subject; and
applying a second near-infrared light having a central wavelength of 760-860 nm to the head of the subject;
wherein the second near-infrared light is applied simultaneously or alternately with the first near-infrared light, and
wherein the first near-infrared light and the second near-infrared light are applied at a pulse frequency of 8-12 Hz with a duty cycle of 50%.