| CPC A61M 25/04 (2013.01) [A61M 25/0074 (2013.01); A61M 25/0084 (2013.01); A61M 2025/0004 (2013.01); A61M 2210/12 (2013.01)] | 24 Claims |

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1. A guide catheter for placement within a blood vessel, comprising:
an outer sheath having a distal end;
an inner sheath having a distal end, the inner sheath being axially translatable and fitting within the outer sheath; and
an expansile anchor mechanism deployable between collapsed and expanded configurations by axially translating the inner and other sheaths relative to one another,
wherein the expansile anchor mechanism comprises a distal end coupled to the distal end of the outer sheath and a proximal end coupled to the distal end of the inner sheath, and
wherein the expansile anchor mechanism comprises a fluid permeable tubular mesh braid and an impermeable elastomeric membrane covering at least a portion of the tubular mesh braid to stabilize a distal tip of the guide catheter to provide support for forward advancement of coaxially inserted devices, catheters, and/or wires through the blood vessel to the distal tip of the guide catheter when the expansile anchor mechanism is in the expanded configuration within the blood vessel.
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