US 12,440,609 B2
Moulded polyurethane hydrogels
Robert Gorkin, III, Sydney (AU); Simon Cook, Sydney (AU); and David Shepherd, Sydney (AU)
Assigned to Eudaemon Technologies Pty Ltd., Sydney (AU)
Appl. No. 17/622,938
Filed by Eudaemon Technologies Pty Ltd., Neutral Bay (AU)
PCT Filed Jun. 27, 2020, PCT No. PCT/AU2020/050671
§ 371(c)(1), (2) Date Dec. 27, 2021,
PCT Pub. No. WO2020/257880, PCT Pub. Date Dec. 30, 2020.
Claims priority of application No. 2019902307 (AU), filed on Jun. 28, 2019.
Prior Publication US 2022/0226547 A1, Jul. 21, 2022
Int. Cl. A61L 31/14 (2006.01); A61L 31/06 (2006.01); B29C 41/00 (2006.01); B29C 41/14 (2006.01); B29C 41/22 (2006.01); B29C 71/00 (2006.01); B29K 75/00 (2006.01); C08G 18/75 (2006.01); C08J 3/075 (2006.01); C08J 5/18 (2006.01); B29L 31/00 (2006.01)
CPC A61L 31/145 (2013.01) [A61L 31/06 (2013.01); B29C 41/003 (2013.01); B29C 41/14 (2013.01); B29C 41/22 (2013.01); B29C 71/0009 (2013.01); C08G 18/758 (2013.01); C08J 3/075 (2013.01); C08J 5/18 (2013.01); A61L 2400/10 (2013.01); B29K 2075/00 (2013.01); B29L 2031/7538 (2013.01); C08J 2375/06 (2013.01); C08J 2375/08 (2013.01)] 34 Claims
OG exemplary drawing
 
1. A method of producing a moulded polyurethane hydrogel, the method comprising:
forming a first solution of at least one polyurethane having a molecular weight of between about 40000 to about 500000 in a water: organic polar solvent comprising less than about 40% (v/v) water;
applying a layer of the first solution to a mould;
drying the layer of the first solution to form a polyurethane film on the mould; and
contacting the polyurethane film with a swelling agent under conditions such that the film forms a polyurethane hydrogel with a swelling agent content of between about 1% to about 95%,
wherein the polyurethane consists of —CH2—(CH2—O—CH2)n—CH2—[O—OCHN(C6H10)CH2(C6H10)NHCO—O—(CH2CH2—O—CH2CH2)—O—OCHN(C6H10) CH2 (C6H10)NHCO—NH—(C6H10)CH2 (C6H10)NHCO—O—CH2CH2—O—CH2CH2—O—OCHN(C6H10)CH2(C6H10)NHCO—O]m—CH2—(CH2—O—CH2)n—CH2 and methyl and/or hydroxyl end groups, and wherein
n is an average independently selected from any number from 1 to 35; and
m is an average independently selected from any number from 15 to 500.