US 12,440,565 B1
Dendritic cell preparation and preparation method thereof
Xudong Cheng, Beijing (CN)
Assigned to ZSKY BIOTECH INC., Beijing (CN)
Filed by ZSKY BIOTECH INC., Beijing (CN)
Filed on Sep. 30, 2024, as Appl. No. 18/901,784.
Claims priority of application No. 202410674814.7 (CN), filed on May 28, 2024; and application No. 202410675731.X (CN), filed on May 28, 2024.
Int. Cl. A61K 40/42 (2025.01); A61K 40/19 (2025.01); A61P 35/00 (2006.01); C12N 5/0784 (2010.01)
CPC A61K 40/428 (2025.01) [A61K 40/19 (2025.01); A61P 35/00 (2018.01); C12N 5/0639 (2013.01); C12N 2501/22 (2013.01); C12N 2501/2304 (2013.01); C12N 2501/25 (2013.01); C12N 2501/51 (2013.01); C12N 2501/52 (2013.01); C12N 2502/30 (2013.01)] 17 Claims
 
1. A novel dendritic cell preparation, comprising PD-L1 negative dendritic cells and dendritic cells with CD40 agonists bound to the cell surface, wherein the surface of PD-L1 negative dendritic cells in the preparation is bound to PD-L1 antibodies.