US 12,440,548 B2
Streptococcus pneumoniae capsular polysaccharides and immunogenic conjugate thereof
Hun Kim, Suwon-si (KR); Dong Soo Ham, Suwon-si (KR); Jin-Hwan Shin, Seoul (KR); Kyung-Jun An, Seoul (KR); and Sung-Hyun Kim, Yongin-si (KR)
Assigned to SK BIOSCIENCE CO., LTD., Seongnam-si (KR)
Filed by SK BIOSCIENCE CO., LTD., Seongnam-si (KR)
Filed on Mar. 7, 2024, as Appl. No. 18/598,439.
Application 18/598,439 is a division of application No. 17/047,563, granted, now 11,951,162, previously published as PCT/KR2019/004717, filed on Apr. 18, 2019.
Claims priority of application No. 10-2018-0045245 (KR), filed on Apr. 18, 2018; application No. 10-2018-0045246 (KR), filed on Apr. 18, 2018; application No. 10-2018-0045247 (KR), filed on Apr. 18, 2018; and application No. 10-2018-0045248 (KR), filed on Apr. 18, 2018.
Prior Publication US 2024/0207384 A1, Jun. 27, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 39/09 (2006.01); A61K 47/61 (2017.01); C07K 14/31 (2006.01); C07K 14/315 (2006.01)
CPC A61K 39/092 (2013.01) [A61K 47/61 (2017.08); C07K 14/315 (2013.01)] 8 Claims
 
1. An immunogenic composition comprising a Streptococcus pneumoniae serotype 20 glycoconjugate in which a capsular polysaccharide from Streptococcus pneumoniae serotype 20 is conjugated to a carrier protein,
wherein the capsular polysaccharide is conjugated to the protein in a state where the capsular polysaccharide is activated to have a degree of oxidation of 4-16 and a molecular weight is 400-800 kDa.