US 12,440,540 B2
IL-2 orthologs and methods of use
Paul-Joseph Penaflor-Aspuria, Redwood City, CA (US); Scott Alan McCauley, Menlo Park, CA (US); Martin Oft, Palo Alto, CA (US); and Steve Kauder, Menlo Park, CA (US)
Assigned to Synthekine, Inc., Menlo Park, CA (US)
Filed by Synthekine, Inc., Menlo Park, CA (US)
Filed on Mar. 23, 2023, as Appl. No. 18/189,116.
Application 18/189,116 is a continuation of application No. 17/119,923, filed on Dec. 11, 2020, granted, now 11,648,296.
Claims priority of provisional application 62/948,066, filed on Dec. 13, 2019.
Prior Publication US 2023/0381278 A1, Nov. 30, 2023
Int. Cl. C12N 15/85 (2006.01); A61K 38/20 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 14/55 (2006.01); C12N 5/0783 (2010.01)
CPC A61K 38/2013 (2013.01) [A61K 39/3955 (2013.01); A61K 39/4611 (2023.05); A61K 39/464 (2023.05); C07K 14/55 (2013.01); C12N 5/0636 (2013.01); C12N 15/85 (2013.01)] 8 Claims
 
1. A nucleic acid sequence encoding a human IL2 (hIL2) ortholog polypeptide consisting of the amino acid sequence set forth in SEO ID NO:20.