	US 12,440,533 B2
	Collagen hydrolysate composition for reducing joint pain after exercise
Janne Prawitt, Ghent (BE); Sebastiaan Johannes Wilhelmus Van Der Steen, Ghent (BE); Sara De Pelsmaeker, Ghent (BE); Willem Meindert Pelser, Ghent (BE); Frederik Beekmans, Ghent (BE); and Hugues Moreau, Ghent (BE)
Assigned to ROUSSELOT B.V., Ghent (BE)
Appl. No. 18/861,616
Filed by ROUSSELOT B.V., Ghent (BE)
PCT Filed May 3, 2023, PCT No. PCT/EP2023/061722 § 371(c)(1), (2) Date Oct. 30, 2024, PCT Pub. No. WO2023/213909, PCT Pub. Date Nov. 9, 2023.
Claims priority of application No. 2022/5336 (BE), filed on May 4, 2022.
Prior Publication US 2025/0114427 A1, Apr. 10, 2025
Int. Cl. A61K 38/01 (2006.01); A61K 31/198 (2006.01); A61K 31/401 (2006.01); A61K 31/737 (2006.01); A61K 45/06 (2006.01); A61P 19/02 (2006.01); C07K 14/78 (2006.01)

CPC A61K 38/014 (2013.01) [A61K 31/198 (2013.01); A61K 31/401 (2013.01); A61K 31/737 (2013.01); A61K 45/06 (2013.01); A61P 19/02 (2018.01); C07K 14/78 (2013.01)]

9 Claims

1. A method for ameliorating joint pain in a subject after exercise, comprising:

administering a composition to the subject,

wherein the composition comprises 10-40 wt. % chondroitin sulfate and 60-90 wt. % collagen hydrolysate, calculated on the total weight of the chondroitin sulfate and the collagen hydrolysate, and

wherein the collagen hydrolysate is derived from the hydrolysis of a mixture of collagen comprising type I, type II, and type Ill collagen such that the collagen hydrolysate comprises hydroxyproline and hydroxylysine in a molar ratio (hydroxyproline:hydroxylysine) of more than 8 and less than 15.