	US 12,440,509 B2
	Application of sulfated polysaccharides in resisting novel coronavirus
Beiwei Zhu, Dalian (CN); Shuang Song, Dalian (CN); Xiuping Dong, Dalian (CN); Chengrong Wen, Dalian (CN); Chunqing Ai, Dalian (CN); Dayong Zhou, Dalian (CN); Hang Qi, Dalian (CN); Libo Qi, Dalian (CN); Dongmei Li, Dalian (CN); and Jingfeng Yang, Dalian (CN)
Assigned to Dalian Polytechnic University, Dalian (CN)
Filed by Dalian Polytechnic University, Dalian (CN)
Filed on Jan. 4, 2022, as Appl. No. 17/567,945.
Application 17/567,945 is a continuation of application No. PCT/CN2020/112597, filed on Aug. 31, 2020.
Claims priority of application No. 202010560842.8 (CN), filed on Jun. 18, 2020; application No. 202010561812.9 (CN), filed on Jun. 18, 2020; and application No. 202010561815.2 (CN), filed on Jun. 18, 2020.
Prior Publication US 2022/0125827 A1, Apr. 28, 2022
Int. Cl. A61K 31/737 (2006.01); A23L 29/256 (2016.01); A61K 9/00 (2006.01); A61K 31/731 (2006.01); A61P 11/00 (2006.01); A61P 31/14 (2006.01); B01D 46/00 (2022.01)

CPC A61K 31/737 (2013.01) [A23L 29/256 (2016.08); A61K 9/0073 (2013.01); A61K 31/731 (2013.01); A61P 11/00 (2018.01); A61P 31/14 (2018.01); B01D 46/00 (2013.01)]

6 Claims

1. A method of inhibiting a novel coronavirus SARS-COV-2 infection in a subject in need thereof, comprising:

providing sea cucumber polysaccharides to the subject, thereby binding of the sea cucumber polysaccharides to an S protein on the surface of SARS-COV-2 of the subject to prevent the SARS-COV-2 virus from invading body cells, wherein the sea cucumber polysaccharides comprise sea cucumber sulfated fucan and sea cucumber fucosylated chondroitin sulfate.