US 12,440,508 B2
Methods and compositions for therapeutic skin treatments in dermatological procedures affecting skin's barrier
Steven M. Hernandez, Blue Point, NY (US)
Assigned to Topix Pharmaceuticals, Inc., North Amityville, NY (US)
Filed by Topix Pharmaceuticals, Inc., North Amityville, NY (US)
Filed on Dec. 6, 2023, as Appl. No. 18/530,920.
Application 18/530,920 is a continuation of application No. 17/497,436, filed on Oct. 8, 2021, granted, now 11,865,138.
Claims priority of provisional application 63/089,903, filed on Oct. 9, 2020.
Prior Publication US 2024/0100085 A1, Mar. 28, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/728 (2006.01); A61K 9/00 (2006.01); A61K 31/19 (2006.01); A61K 31/375 (2006.01); A61K 45/06 (2006.01); A61P 1/02 (2006.01); A61P 17/02 (2006.01)
CPC A61K 31/728 (2013.01) [A61K 9/0014 (2013.01); A61K 9/0021 (2013.01); A61K 31/19 (2013.01); A61K 31/375 (2013.01); A61K 45/06 (2013.01); A61P 1/02 (2018.01); A61P 17/02 (2018.01)] 15 Claims
 
1. A method, comprising:
applying a therapeutically effective amount of a dermatological formulation to the skin, wherein the dermatological formulation comprises sodium hyaluronate, an emulsifier, ascorbic acid, glycolic acid, and lactic acid, wherein the sodium hyaluronate is a solution of honeycomb array sodium hyaluronate and wherein the sodium hyaluronate is included in at least about 1% (w/w) and each of the ascorbic acid, glycolic acid, and lactic acid is included in an amount of 1 ppm to 100 ppm; and
performing a dermatological procedure on the skin.