	US 12,440,478 B2
	Process for preparing a potent thiazole compound, pharmaceutical formulation and uses thereof
Parul Ganju, Pune (IN); Sudhanand Prasad, Pune (IN); Mahesh Kumar Verma, Pune (IN); Kashinath Komirishetty, Pune (IN); and Annie Richharia, Pune (IN)
Assigned to AHAMMUNE BIOSCIENCES PRIVATE LIMITED, Pune (IN)
Appl. No. 17/050,431
Filed by AHAMMUNE BIOSCIENCES PRIVATE LIMITED, Pune (IN)
PCT Filed Apr. 26, 2019, PCT No. PCT/IB2019/053459 § 371(c)(1), (2) Date Oct. 24, 2020, PCT Pub. No. WO2019/207548, PCT Pub. Date Oct. 31, 2019.
Claims priority of application No. 201821015990 (IN), filed on Apr. 27, 2018.
Prior Publication US 2021/0275502 A1, Sep. 9, 2021
Int. Cl. A61K 31/426 (2006.01); A61K 9/06 (2006.01); A61K 47/10 (2017.01); A61K 47/32 (2006.01); A61P 17/00 (2006.01); A61P 29/00 (2006.01); C07D 277/28 (2006.01)

CPC A61K 31/426 (2013.01) [A61K 9/06 (2013.01); A61K 47/10 (2013.01); A61K 47/32 (2013.01); A61P 17/00 (2018.01); A61P 29/00 (2018.01); C07D 277/28 (2013.01)]

14 Claims

1. A topical formulation comprising N-[2-[2-(4-chlorophenyl)-4-thiazolyl]ethyl]-butanamide or pharmaceutically acceptable salts thereof as the active compound in an amount of 0.1-90 wt %, a solvent, a gelling agent, a permeation enhancer and an excipient: wherein the topical formulation is in the form of a gel, ointment, cream, lotion, spray or foam.