US 12,440,462 B2
Compositions and methods for remediating chemical warfare agent exposed skin
Scott Noblitt, Fort Collins, CO (US); and Edwin Neas, Nunn, CO (US)
Assigned to Armis Biopharma, Inc., Fort Collins, CO (US)
Filed by Armis Biopharma, Inc., Fort Collins, CO (US)
Filed on May 21, 2021, as Appl. No. 17/326,507.
Application 17/326,507 is a continuation in part of application No. PCT/US2021/012540, filed on Jan. 7, 2021.
Application PCT/US2021/012540 is a continuation of application No. 16/900,816, filed on Jun. 12, 2020.
Application PCT/US2021/012540 is a continuation of application No. 16/736,546, filed on Jan. 7, 2020, abandoned.
Application 16/900,816 is a continuation in part of application No. 16/736,546, filed on Jan. 7, 2020, abandoned.
Application 16/736,546 is a continuation in part of application No. PCT/US2018/041163, filed on Jul. 7, 2018.
Claims priority of provisional application 63/004,858, filed on Apr. 3, 2020.
Claims priority of provisional application 62/861,810, filed on Jun. 14, 2019.
Claims priority of provisional application 62/530,045, filed on Jul. 7, 2017.
Prior Publication US 2022/0023174 A1, Jan. 27, 2022
Int. Cl. A61K 31/19 (2006.01); A61K 9/06 (2006.01); A61K 31/327 (2006.01); A61K 33/40 (2006.01); A61P 17/02 (2006.01); A61P 39/02 (2006.01)
CPC A61K 31/19 (2013.01) [A61K 9/06 (2013.01); A61K 31/327 (2013.01); A61K 33/40 (2013.01); A61P 17/02 (2018.01); A61P 39/02 (2018.01)] 12 Claims
 
1. A kit for chemical warfare agent decontamination, said kit comprising a chemical warfare agent decontaminating composition, packaged with a synthetic absorbent applicator comprising a non-woven fabric, cloth, mitt or towelette for application of the composition to a wound suffered by an exposed animal subject, an absorbent pad for removal of the composition and any chemical warfare agent from the wound, and a nerve gas antidote packaged for administering to the exposed subject,
wherein the decontaminating composition comprises active decontaminating compounds consisting of:
peracetic acid in an amount ranging from about 1% to about 6% by weight;
hydrogen peroxide in an amount ranging from about 3% to about 15% by weight;
acetic acid in an amount ranging from about 3% to about 15% by weight; and
the molar ratio of hydrogen peroxide to acetic acid ranges from 0.5:1 to about 2:1; and
the decontaminating composition further comprises a stabilizer and ingredients to formulate the composition as an aerosol or liquid spray, application granules, a gel, liquid, lotion or irrigation gel.