US 12,440,452 B2
Ropinirole-containing patch and method for improving skin permeability of ropinirole
Naoyuki Uchida, Tsukuba (JP); and Satoshi Amano, Tsukuba (JP)
Assigned to HISAMITSU PHARMACEUTICAL CO., INC., Tosu (JP)
Appl. No. 18/034,480
Filed by HISAMITSU PHARMACEUTICAL CO., INC., Tosu (JP)
PCT Filed Oct. 21, 2021, PCT No. PCT/JP2021/038892
§ 371(c)(1), (2) Date Apr. 28, 2023,
PCT Pub. No. WO2022/091925, PCT Pub. Date May 5, 2022.
Claims priority of application No. 2020-181280 (JP), filed on Oct. 29, 2020.
Prior Publication US 2024/0016758 A1, Jan. 18, 2024
Int. Cl. A61K 9/70 (2006.01); A61K 31/4045 (2006.01); A61K 47/12 (2006.01)
CPC A61K 9/7084 (2013.01) [A61K 31/4045 (2013.01); A61K 47/12 (2013.01)] 6 Claims
 
1. A ropinirole-containing patch comprising a backing layer and an adhesive agent layer, wherein
the adhesive agent layer comprising:
at least one selected from the group consisting of ropinirole and a pharmaceutically acceptable salt thereof;
at least one sodium carboxylate selected from the group consisting of sodium pentanoate, disodium glutarate, and sodium hexanoate; and
an adhesive agent.