US 12,440,449 B2
Alcohol-resistant drug formulations
Edwin Walsh, Dublin (IE); and Clark Patrick Allphin, Seattle, WA (US)
Assigned to Jazz Pharmaceuticals Ireland Limited, Dublin (IE)
Filed by Jazz Pharmaceuticals Ireland Limited, Dublin (IE)
Filed on Feb. 11, 2022, as Appl. No. 17/670,078.
Application 17/670,078 is a continuation of application No. 16/688,797, filed on Nov. 19, 2019, granted, now 11,400,052.
Claims priority of provisional application 62/769,380, filed on Nov. 19, 2018.
Claims priority of provisional application 62/769,382, filed on Nov. 19, 2018.
Prior Publication US 2022/0160640 A1, May 26, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 9/28 (2006.01); A61K 45/06 (2006.01)
CPC A61K 9/2866 (2013.01) [A61K 9/2846 (2013.01); A61K 45/06 (2013.01)] 23 Claims
 
1. A pharmaceutical formulation comprising a film coated drug carrier core, wherein the drug carrier core comprises at least one therapeutic agent selected from gamma hydroxybutyrate (GHB), a pharmaceutically acceptable salt of GHB, or a prodrug of GHB, and wherein the film coating comprises a polymer blend of ethyl cellulose and a polymethacrylate polymer disposed over the drug carrier core; and
wherein the polymer blend provides an enteric dissolution.