	US 12,440,448 B2
	Powder, wound-covering material, adhesion prevention material, hemostatic material, and production method for powder
Tetsushi Taguchi, Tsukuba (JP)
Assigned to NATIONAL INSTITUTE FOR MATERIALS SCIENCE, Ibaraki (JP)
Appl. No. 17/414,510
Filed by NATIONAL INSTITUTE FOR MATERIALS SCIENCE, Tsukuba (JP)
PCT Filed Dec. 20, 2019, PCT No. PCT/JP2019/050157 § 371(c)(1), (2) Date Jun. 16, 2021, PCT Pub. No. WO2020/137903, PCT Pub. Date Jul. 2, 2020.
Claims priority of application No. 2018-243101 (JP), filed on Dec. 26, 2018.
Prior Publication US 2022/0062179 A1, Mar. 3, 2022
Int. Cl. A61K 9/16 (2006.01); A61K 9/19 (2006.01); A61L 26/00 (2006.01)

CPC A61K 9/1658 (2013.01) [A61K 9/1682 (2013.01); A61K 9/19 (2013.01); A61L 26/0038 (2013.01); A61L 2400/04 (2013.01)]

17 Claims

1. A powder comprises particles comprising a crosslinked gelatin derivative, wherein the gelatin derivative has a structure represented by formula (1):

GltnNH-L-CHR¹R² (1)

wherein Gltn represents a gelatin residue; L represents a single bond or a divalent linking group; R¹represents a hydrocarbon group having 1 to 20 carbon atoms; and R²represents a hydrogen atom or a hydrocarbon group having 1 to 20 carbon atoms, and

wherein the particles have an average sphericity of 1.20 or less, and a standard deviation of sphericity of 0.20 or less.