US 12,440,379 B2
Systems and methods to probe ocular structures
Rafael Piestun, Boulder, CO (US); and Kristina Irsch, Paris (FR)
Assigned to The Regents of the University of Colorado, a body corporate, Denver, CO (US); and Sorbonne Université, Paris (FR)
Appl. No. 17/774,729
Filed by The Regents of the University of Colorado, a body corporate, Denver, CO (US); and Sorbonne Université, Paris (FR)
PCT Filed Nov. 5, 2020, PCT No. PCT/US2020/059161
§ 371(c)(1), (2) Date May 5, 2022,
PCT Pub. No. WO2021/092211, PCT Pub. Date May 14, 2021.
Claims priority of provisional application 62/930,816, filed on Nov. 5, 2019.
Prior Publication US 2022/0395394 A1, Dec. 15, 2022
Int. Cl. A61F 9/008 (2006.01); A61B 3/10 (2006.01)
CPC A61F 9/008 (2013.01) [A61B 3/102 (2013.01); A61F 2009/00846 (2013.01)] 23 Claims
OG exemplary drawing
 
1. A method for probing an ocular structure of a living eye, the method comprising:
projecting a light onto the ocular structure using light delivery optics to generate a secondary light that emanates from the ocular structure, wherein the projection of light is temporally synchronized with detection events occurring at a plurality of successive times, wherein naturally occurring eye movement during these times enables illumination of the ocular structure from distinct perspectives;
detecting, via a detector and light collection optics, the secondary light emanating from the ocular structure at the plurality of successive times, wherein the plurality of successive times correspond to natural positional variations of the ocular structure such that different portions of the ocular structure are illuminated different times;
generating at least one measurement comprising depth information of the ocular structure based on the secondary light detected at the plurality of successive times, wherein the at least one measurement is a composite representation derived from the ocular structure illuminated at the plurality of successive times.