US 12,440,378 B1
Devices and systems for cutting, loading, and delivering biologic intraocular implants for increased aqueous outflow and lowering of intraocular pressure
Sean Buxton, Harrison, NY (US); Roderick H. Beaulieu, Harrison, NY (US); Tsontcho Ianchulev, Harrison, NY (US); Daniel Nelsen, Harrison, NY (US); David Robson, Harrison, NY (US); and Joshua Williams, Harrison, NY (US)
Assigned to Iantrek, Inc., Harrison, NY (US)
Filed by Iantrek, Inc., Harrison, NY (US)
Filed on Feb. 13, 2025, as Appl. No. 19/053,243.
Application 19/053,243 is a continuation of application No. 19/100,424, previously published as PCT/US2023/080677, filed on Nov. 21, 2023.
Claims priority of provisional application 63/584,804, filed on Sep. 22, 2023.
Claims priority of provisional application 63/488,920, filed on Mar. 7, 2023.
Claims priority of provisional application 63/427,552, filed on Nov. 23, 2022.
Int. Cl. A61F 9/007 (2006.01); A61F 9/00 (2006.01)
CPC A61F 9/00781 (2013.01) [A61F 9/0017 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A method of treating glaucoma of an eye comprising:
inserting a first implant in a treatment site in an eye, wherein the implant comprises dehydrated, biologically-derived tissue having a first size;
opening a space within the treatment site with the implant due to the dehydrated, biologically-derived tissue of the implant rehydrating in the eye and expanding from the first size to a second size; and
inserting a second implant near the treatment site of the first implant,
wherein the first implant and the second implant are both formed and cut of dehydrated, biologically-derived tissue, wherein the biologically-derived tissue of the first implant is the same as or different from the biologically-derived tissue of the second implant,
wherein the second implant creates a scaffold with the first implant and a reservoir within a target site between the first implant and the second implant, and
wherein the treatment site is between internal eye tissue layers, and wherein opening the space within the treatment site increases outflow of aqueous from an anterior chamber of the eye through the treatment site between the internal eye tissue layers.