US 12,440,373 B2
Device for controlled injection across a variety of material properties
Niki Bayat, Pasadena, CA (US); Adam Griese, Los Angeles, CA (US); Roby Menefee, Los Angeles, CA (US); Rahul Janardhanan, Los Angeles, CA (US); and Jose Ramirez, Denver, CO (US)
Assigned to AESCULATECH, INC., Los Angeles, CA (US)
Appl. No. 18/009,897
Filed by AESCULA TECH, INC., Los Angeles, CA (US)
PCT Filed Jun. 11, 2021, PCT No. PCT/US2021/036931
§ 371(c)(1), (2) Date Dec. 12, 2022,
PCT Pub. No. WO2021/252841, PCT Pub. Date Dec. 16, 2021.
Claims priority of provisional application 63/101,228, filed on Jun. 11, 2020.
Prior Publication US 2023/0233374 A1, Jul. 27, 2023
Int. Cl. A61F 9/00 (2006.01); A61F 9/007 (2006.01); A61L 31/04 (2006.01); A61L 31/14 (2006.01)
CPC A61F 9/0017 (2013.01) [A61F 9/00772 (2013.01); A61L 31/048 (2013.01); A61L 31/145 (2013.01)] 86 Claims
OG exemplary drawing
 
1. An injection device, comprising:
an injection port configured to deliver a shape adaptable material, the injection port comprising a straight, blunt-tipped tube extending between an inlet at a proximal end and an outlet at a distal end, the injection port having a substantially constant diameter along its length and a fixed exposed length of about 1 mm to about 5 mm;
a junction component coupled to a body of the injection device and to the proximal end of the injection port, the junction component comprising a sealed reservoir configured to contain and store the shape adaptable material for ejection through the injection port, the reservoir having a diameter in a range from about 0.1 mm to less than 5 mm and a ratio of the diameter to a primed length from about 1:1000 to about 10:1 the junction component further comprising a linear dispensing channel having a length extending between a first end at a distal end of a barrel of the reservoir and a second end at the inlet of the injection port, the linear dispensing channel comprising an intermediate chamber adjacent to the distal end of the barrel, the intermediate chamber having a barrel diameter in a range of about 25% to about 95% of a barrel diameter of the reservoir; and
an actuation mechanism comprising a stopper that engages with and seals the reservoir, where activation of the actuation mechanism forces the stopper into the reservoir thereby controlling ejection of the shape adaptable material through the injection port, where the actuation mechanism ejects a defined injection volume of the shape adaptable material at a rate of less than 50 μL/second in a range from about 0.1 μL to about 20 μL of the shape adaptable material having a viscosity greater than 3000 cp, the actuation mechanism ejecting the defined injection volume of the shape adaptable material from the reservoir through the injection port by advancing the stopper a predefined length into the reservoir.