US 12,440,180 B2
Systems, devices, and methods for non-invasive image-based plaque analysis and risk determination
James K. Min, Chapel Hill, NC (US); and Hugo Miguel Rodrigues Marques, Lisbon (PT)
Assigned to Cleerly, Inc., Denver, CO (US)
Filed by Cleerly, Inc., Denver, CO (US)
Filed on Feb. 29, 2024, as Appl. No. 18/591,778.
Application 18/591,778 is a continuation of application No. 18/508,098, filed on Nov. 13, 2023.
Application 18/508,098 is a continuation in part of application No. 18/179,921, filed on Mar. 7, 2023.
Claims priority of provisional application 63/478,084, filed on Dec. 30, 2022.
Claims priority of provisional application 63/478,076, filed on Dec. 30, 2022.
Claims priority of provisional application 63/477,985, filed on Dec. 30, 2022.
Claims priority of provisional application 63/477,961, filed on Dec. 30, 2022.
Claims priority of provisional application 63/477,656, filed on Dec. 29, 2022.
Claims priority of provisional application 63/477,640, filed on Dec. 29, 2022.
Claims priority of provisional application 63/477,638, filed on Dec. 29, 2022.
Claims priority of provisional application 63/476,255, filed on Dec. 20, 2022.
Claims priority of provisional application 63/476,251, filed on Dec. 20, 2022.
Claims priority of provisional application 63/476,245, filed on Dec. 20, 2022.
Claims priority of provisional application 63/386,376, filed on Dec. 7, 2022.
Claims priority of provisional application 63/386,297, filed on Dec. 6, 2022.
Claims priority of provisional application 63/385,472, filed on Nov. 30, 2022.
Claims priority of provisional application 63/385,179, filed on Nov. 28, 2022.
Claims priority of provisional application 63/383,904, filed on Nov. 15, 2022.
Claims priority of provisional application 63/383,632, filed on Nov. 14, 2022.
Claims priority of provisional application 63/269,136, filed on Mar. 10, 2022.
Claims priority of provisional application 63/362,856, filed on Apr. 12, 2022.
Claims priority of provisional application 63/364,078, filed on May 3, 2022.
Claims priority of provisional application 63/364,084, filed on May 3, 2022.
Claims priority of provisional application 63/365,381, filed on May 26, 2022.
Claims priority of provisional application 63/368,293, filed on Jul. 13, 2022.
Claims priority of provisional application 63/381,210, filed on Oct. 27, 2022.
Prior Publication US 2025/0000472 A1, Jan. 2, 2025
Int. Cl. A61B 6/00 (2024.01); A61B 6/03 (2006.01); A61B 6/50 (2024.01); G06T 7/00 (2017.01); G06T 7/62 (2017.01); G06V 10/22 (2022.01); G06V 10/26 (2022.01); G16H 30/40 (2018.01); G16H 50/20 (2018.01)
CPC A61B 6/5217 (2013.01) [A61B 6/032 (2013.01); A61B 6/503 (2013.01); A61B 6/504 (2013.01); A61B 6/507 (2013.01); A61B 6/5229 (2013.01); G06T 7/0012 (2013.01); G06T 7/62 (2017.01); G06V 10/22 (2022.01); G06V 10/26 (2022.01); G16H 30/40 (2018.01); G16H 50/20 (2018.01); G06T 2207/10081 (2013.01); G06T 2207/20076 (2013.01); G06T 2207/30048 (2013.01); G06T 2207/30104 (2013.01); G06V 2201/031 (2022.01)] 20 Claims
OG exemplary drawing
 
1. A computer-implemented method of identifying a medical image based at least in part on quantitative volumetric assessment of the medical image, the method comprising:
accessing, by a computer system, a medical image of a subject, wherein the medical image of the subject is obtained non-invasively;
analyzing, by the computer system, the medical image of the subject to identify a volume of interest;
performing, by the computer system, quantitative volumetric assessment of the volume of interest, wherein the quantitative volumetric assessment comprises:
identifying each pixel or voxel within the volume of interest;
determining a plaque density of each identified pixel or voxel within the volume of interest; and
mapping a plaque density distribution based on the plaque density of each identified pixel or voxel within the volume of interest;
comparing, by the computer system, the mapped plaque density distribution of the quantitative volumetric assessment of the volume of interest to at least one plaque density distribution of one or more quantitative volumetric assessments of pre-existing medical images to determine whether the quantitative volumetric assessment of the volume of interest matches the one or more quantitative volumetric assessments of pre-existing medical images; and
when a match is determined:
associating, by the computer system, the quantitative volumetric assessment of the volume of interest to one or more quantitative volumetric assessments of pre-existing medical images;
identifying, by the computer system, the medical image to be identical to the one or more pre-existing medical images;
retrieving, by the computer system, a medical report of a subject associated with the one or more pre-existing medical images; and
associating, by the computer system, the retrieved medical report of the subject with the medical image,
wherein the computer system comprises a computer processor and an electronic storage medium.