| CPC A61B 5/7275 (2013.01) [A61B 5/0205 (2013.01); A61B 5/412 (2013.01); G16H 50/50 (2018.01); A61B 5/021 (2013.01); A61B 5/024 (2013.01); A61B 5/0816 (2013.01)] | 18 Claims |

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1. A non-transitory computer-readable media having computer-executable instructions embodied thereon that when executed by one or more processors of a system for forecasting an emergent acute inflammatory condition or event in a patient, provide a decision support system for predicting emergence of an acute inflammatory condition, the instructions comprising:
acquiring, by the one or more processors, using one or more patient monitoring devices comprising a sensor, a plurality of measurements of vital signs for the patient, the plurality of measurements of vital signs acquired over a timespan and not acquired on a periodic basis;
constructing, by the one or more processors, a vital signs time series using the plurality of measurements of vital signs;
determining, by the one or more processors, a likelihood of the patient experiencing an occurrence of the acute inflammatory condition over a future timeframe;
based on the determined likelihood, automatically initiating, by the one or more processors, a response action indicating a patient's condition, and automatically modifying a computer code executed in a healthcare software program for treating the patient by increasing a frequency of obtaining physiological measurements of the patient or by increasing a sensitivity of monitoring physiological changes in the patient, thereby transforming the healthcare software program; and
determining a linear model and a cusp catastrophe model based on the vital signs time series.
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