US 12,440,112 B2
System and method for leak correction and normalization of in-ear pressure measurement for hemodynamic monitoring
Anna Barnacka, Cambridge, MA (US); Jal Panchal, Everett, MA (US); Martin D. Ring, Ashland, MA (US); and Pratistha Shakya, Auburn, MA (US)
Assigned to MINDMICS, INC, Cambridge, MA (US)
Filed by Anna Barnacka, Cambridge, MA (US); Jal Panchal, Everett, MA (US); Martin D. Ring, Ashland, MA (US); and Pratistha Shakya, Auburn, MA (US)
Filed on Jun. 25, 2021, as Appl. No. 17/359,001.
Claims priority of provisional application 63/044,056, filed on Jun. 25, 2020.
Prior Publication US 2021/0401311 A1, Dec. 30, 2021
Int. Cl. A61B 5/021 (2006.01); A61B 5/00 (2006.01); H04R 1/10 (2006.01)
CPC A61B 5/02116 (2013.01) [A61B 5/6817 (2013.01); A61B 5/7203 (2013.01); H04R 1/1016 (2013.01); A61B 2562/0204 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A biosensor system, comprising:
an acoustical assembly including an earbud system that is configured to form an earbud seal with an ear canal of an individual, wherein the earbud system includes an earbud with an in-ear acoustic sensor that detects acoustic signals from a body of the individual in the ear canal over time, and wherein the acoustic signals include audible signals and infrasonic signals;
a data analysis system that receives the acoustic signals from the earbud system, identifies hemodynamic pressure signals included within the infrasonic signals, and identifies signal characteristics of the hemodynamic pressure signals over time; and
a user device that includes a processor, a memory and at least one application that executes in the memory, wherein the user device is configured to be carried by the individual, and wherein the user device is in communication with the earbud system and the data analysis system;
wherein the data analysis system detects leaky pressure signals, which are reduced amplitude versions of the hemodynamic pressure signals caused by leaks in the earbud seal, and computes corrected versions of the leaky pressure signals based upon changes to the signal characteristics of the hemodynamic pressure signals over time;
wherein the data analysis system is configured to:
compute hemodynamic measurements of the individual from at least the corrected versions of the leaky pressure signals, the hemodynamic measurements including blood pressure (bp) measurements;
include the hemodynamic measurements including the bp measurements in messages; and
send the messages to the individual via the user device, which reports the hemodynamic measurements to the individual; and
wherein the data analysis system additionally sends the messages including the hemodynamic measurements to a medical records database to update medical records of the individual.