CPC C12Q 1/689 (2013.01) [A23L 33/21 (2016.08); A23L 33/30 (2016.08); A23L 33/40 (2016.08); A61K 35/74 (2013.01); A61K 35/741 (2013.01); A61P 3/04 (2018.01); A61P 3/06 (2018.01); A23V 2002/00 (2013.01); A23V 2200/332 (2013.01)] | 3 Claims |
1. A method of promoting weight loss in a patient wherein the patient has been identified as having at least one of: (a) a gut microbiota with a relative abundance of log 10 (Prevotella spp.) of greater than −3, (b) a gut microbiota with a relative abundance of log 10 (Prevotella spp./Bacteroides spp.) of greater than −2, (c) a gut microbiota with a relative abundance of Log 10 (Prevotella spp./Bacteroidetes all) of greater than −2, and (d) a gut microbiota with a relative abundance of Log 10(Bacteroidetes all/Bacteroides spp.) of greater than 0, comprising the steps of;
(a) determining the patient's fasting plasma glucose (FPG) and fasting insulin level (FI); and
(b) administering to the patient a predetermined diet, wherein
(i) the patient's FPG is less than about 90 mg/dL, the patient's FI is below about 9.5 uU/mL and the predetermined diet is Diet 1;
(ii) the patient's FPG is less than about 90 mg/dL, the patient's FI is above about 13 uU/mL, and the predetermined diet is Diet 2;
(iii) the patient's FPG is between about 90 and 100 mg/dL, the patient's FI is above about 13 uU/mL and the predetermined diet is Diet 4;
(iv) the patient's FPG is between about 100 and 115 mg/dL, the patient's FI is below about 9.5 uU/mL and the predetermined diet is Diet 5;
(v) the patient's FPG is between about 100 and 115 mg/dL, the patient's FI is above about 13 uU/mL and the predetermined diet is Diet 6;
(vi) vi the patient's FPG is between about 115 and 125 mg/dL, the patient's FI is below about 9.5 uU/mL and the predetermined diet is Diet 7;
(vii) vii the patient's FPG is between about 115 and 125 mg/dL, the patient's FI is above about 13 uU/mL and the predetermined diet is Diet 8;
(viii) the patient's FPG is greater than about 125 mg/dL, the patient's FI is below about 9.5 uU/mL and the predetermined diet is Diet 9;
(ix) the patient's FPG is greater than about 125 mg/dL, the patient's FI is above about 13 uU/mL and the predetermined diet is Diet 10;
(x) the patient's FPG is less than about 90 mg/dL, the patient's FI is between about 9.5 to about 13 uU/mL, and the predetermined diet is Diet 1 or Diet 2;
(xi) the patient's FPG is between about 90 and 100 mg/dL, the patient's FI is between about 9.5 to about 13 uU/mL, and the predetermined diet is Diet 4;
(xii) the patient's FPG is between about 100 and 115 mg/dL, the patient's FI is between about 9.5 to about 13 uU/mL, and the predetermined diet is Diet 5 or Diet 6;
(xiii) the patient's FPG is between about 115 and 125 mg/dL, the patient's FI is between about 9.5 to about 13 uU/mL, and the predetermined diet is Diet 7 or Diet 8; or
(xiv) the patient's FPG is greater than about 125 mg/dL, the patient's FI is between about 9.5 to about 13 uU/mL, and the predetermined diet is Diet 9 or Diet 10;
wherein diets 1, 2 and 4-10 are defined in the table below:
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