US 12,110,528 B2
Cell hydrolysate composition from cultivated cells and applications thereof
Po San Mario Chin, Hong Kong (CN); Kai Yi Carrie Chan, Hong Kong (CN); and Chun Hei Poon, Hong Kong (CN)
Assigned to Avant Meats Company Limited, Hong Kong (CN)
Filed by Avant Meats Company Limited, Hong Kong (CN)
Filed on Feb. 11, 2022, as Appl. No. 17/670,288.
Application 17/670,288 is a division of application No. 17/243,493, filed on Apr. 28, 2021, granted, now 11,306,342.
Application 17/243,493 is a continuation of application No. PCT/IB2020/060727, filed on Nov. 14, 2020.
Claims priority of provisional application 63/173,332, filed on Apr. 9, 2021.
Claims priority of provisional application 62/942,568, filed on Dec. 2, 2019.
Prior Publication US 2022/0162662 A1, May 26, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 38/18 (2006.01); A23J 3/04 (2006.01); A23J 3/34 (2006.01); A23L 33/18 (2016.01); A61K 8/65 (2006.01); A61K 38/19 (2006.01); A61K 38/39 (2006.01); A61Q 19/00 (2006.01); C07K 1/12 (2006.01); C12P 21/06 (2006.01)
CPC C12P 21/06 (2013.01) [A23J 3/04 (2013.01); A23J 3/342 (2013.01); A23L 33/18 (2016.08); A61K 8/65 (2013.01); A61K 38/18 (2013.01); A61K 38/39 (2013.01); A61Q 19/00 (2013.01); C07K 1/12 (2013.01); A23V 2002/00 (2013.01)] 3 Claims
 
1. An artificially generated cell hydrolysate composition, the composition comprising:
(i) a mixture of polypeptide fragments from collagen 1 α1 comprising at least 56 sequences selected from the group consisting of SEQ ID NOS: 1-112;
(ii) a mixture of polypeptide fragments from collagen 1 β1 comprising at least 51 sequences selected from the group consisting of SEQ ID NOs: 113-214;
(iii) a mixture of polypeptide fragments from connective tissue growth factor (CTGF) comprising at least 17 sequences selected from the group consisting of SEQ ID NOs: 215-249;
(iv) a mixture of protein polypeptides and/or polypeptide fragments from Decorin comprising at least 18 sequences selected from the group consisting of SEQ ID NOs: 250-285;
wherein the polypeptide fragments are from an in vitro cell culture ; and
wherein the purity of the polypeptide fragments in the artificially generated cell hydrolysate composition is higher than that in a cell hydrolysate obtained from an animal tissue or a plant tissue.