Michael A. Crowe, Singapore (SG); Oscar Alvizo, Fremont, CA (US); Behnaz Behrouzian, Sunnyvale, CA (US); Yong Koy Bong, Singapore (SG); Steven J. Collier, Concord, MA (US); Anupam Gohel, Bekasi (ID); Jagadeesh Mavinahalli, Maharashtra (IN); Naga K. Modukuru, Singapore (SG); Emily Mundorff, Garden City, NY (US); Derek J. Smith, Singapore (SG); Shiwei Song, Singapore (SG); and Wan Lin Yeo, Singapore (SG)
Assigned to Codexis, Inc., Redwood City, CA (US)
Filed by Codexis Inc., Redwood City, CA (US)
Filed on Mar. 17, 2021, as Appl. No. 17/204,189.
Application 15/179,503 is a division of application No. 14/692,964, filed on Apr. 22, 2015, granted, now 9,388,391, issued on Jul. 12, 2016.
Application 14/692,964 is a division of application No. 13/695,856, granted, now 9,040,262, issued on May 26, 2015, previously published as PCT/US2011/035194, filed on May 4, 2011.
Application 17/204,189 is a continuation of application No. 16/712,431, filed on Dec. 12, 2019, granted, now 10,995,320.
Application 16/712,431 is a continuation of application No. 16/032,319, filed on Jul. 11, 2018, granted, now 10,544,400, issued on Jan. 28, 2020.
Application 16/032,319 is a continuation of application No. 15/478,466, filed on Apr. 4, 2017, granted, now 10,053,673, issued on Aug. 21, 2018.
Application 15/478,466 is a continuation of application No. 15/179,503, filed on Jun. 10, 2016, granted, now 9,644,189, issued on May 9, 2017.
Claims priority of provisional application 61/331,245, filed on May 4, 2010.
Prior Publication US 2021/0222134 A1, Jul. 22, 2021
1. A non-naturally occurring ketoreductase polypeptide having ketoreductase activity, comprising an amino acid sequence that has at least 95% sequence identity to SEQ ID NO: 168, wherein the residue at position 40 is arginine.