US 12,109,565 B2
Microfluidic device and a method for provision of emulsion droplets
Thomas Kvist, Roskilde (DK); Soléne Cherre, Vimm (DK); and Marie Just Mikkelsen, Brønshøj (DK)
Assigned to SAMPLIX APS, Birkerod (DK)
Appl. No. 17/426,554
Filed by SAMPLIX APS, Herlev (DK)
PCT Filed Jan. 31, 2020, PCT No. PCT/EP2020/052409
§ 371(c)(1), (2) Date Jul. 28, 2021,
PCT Pub. No. WO2020/157269, PCT Pub. Date Aug. 6, 2020.
Claims priority of application No. 19154947 (EP), filed on Jan. 31, 2019.
Prior Publication US 2022/0105515 A1, Apr. 7, 2022
Int. Cl. B01L 3/00 (2006.01)
CPC B01L 3/502769 (2013.01) [B01L 2200/0673 (2013.01); B01L 2300/0883 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A microfluidic device comprising:
an emulsification section comprising one or more emulsification units; and a container section comprising one or more groups of containers comprising
one group of containers for each emulsification unit;
each emulsification unit comprising a fluid conduit network comprising: a plurality of supply conduits comprising a primary supply conduit and a secondary supply conduit;
a transfer conduit; and
a first fluid junction providing fluid communication between the primary supply conduit, the secondary supply conduit, and the transfer conduit; each group of containers comprising a plurality of containers comprising an intermediate chamber, a collection container, and one or more supply containers comprising a secondary supply container,
the secondary supply container defining a secondary supply cavity,
the secondary supply container comprising a secondary orifice extending from the secondary supply cavity and a primary orifice extending from the secondary supply cavity,
the collection container being in fluid communication with the transfer conduit of the corresponding emulsification unit via a collection orifice of the collection container,
the secondary supply container being in fluid communication with the secondary supply conduit of the corresponding emulsification unit via the secondary orifice,
the secondary supply container being in fluid communication with the intermediate chamber of the same group of containers via the primary orifice, the intermediate chamber being in fluid communication with the first fluid junction of the corresponding emulsification unit via the primary supply conduit of the corresponding emulsification unit.