US 12,109,411 B2
Systems and methods for detecting fault conditions in electroporation therapy
John Rodriguez, Vista, CA (US); Jason Jin, Irvine, CA (US); Brandon Dang Phung, San Diego, CA (US); Wesley Joel Ericson, Wyoming, MN (US); Jodie Marie Houdek, Forest Lake, MN (US); Jonathan Joseph McIntosh, Centerville, MN (US); Carlos E. Gonzalez, Firth, ID (US); and Anthony Steven Nault, New Brighton, MN (US)
Assigned to GRAND DECADE DEVELOPMENTS LIMITED, Hong Kong (HK)
Filed by OncoSec Medical Incorporated, San Diego, CA (US)
Filed on Jun. 23, 2021, as Appl. No. 17/304,605.
Application 17/304,605 is a continuation of application No. 16/269,022, filed on Feb. 6, 2019, granted, now 11,071,860.
Prior Publication US 2021/0353938 A1, Nov. 18, 2021
Int. Cl. A61N 1/32 (2006.01); A61B 18/14 (2006.01); A61N 1/04 (2006.01); A61B 18/00 (2006.01)
CPC A61N 1/327 (2013.01) [A61B 18/1477 (2013.01); A61N 1/0412 (2013.01); A61B 2018/00613 (2013.01); A61B 2018/00702 (2013.01); A61B 2018/00767 (2013.01); A61N 1/0476 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A system for electroporating cells in a tissue using a set of voltage pulses generated based on a voltage supply, the system comprising:
a first monitor circuitry, wherein the first monitor circuitry is in electrical communication with at least one of a voltage generation circuitry that is coupled to a capacitor charge circuitry or an electroporation electrode (EPE) circuitry, and wherein the first monitor circuitry is configured to:
receive a first set of monitor signals,
detect a first fault condition based on the first set of monitor signals,
in response to a detection of the first fault condition, transmit first instructions configured to cause termination of electroporation; and
a second monitor circuitry, wherein the second monitor circuitry is in electrical communication with at least one of the voltage generation circuitry or the EPE circuitry, and wherein the second monitor circuitry is configured to:
receive a second set of monitor signals,
detect a second fault condition based on the second set of monitor signals,
in response to a detection of the second fault condition, transmit second instructions configured to cause termination of electroporation,
wherein the second set of monitor signals is based on the first set of monitor signals, wherein the first set of monitor signals is a set of analog monitor signals, wherein the second set of monitor signals is a set of digital monitor signals.