	US 12,109,285 B2
	Zinc phosphate complex for oral care
Baohua Qiao, Howell, NJ (US); Long Pan, Somerset, NJ (US); Gregory Szewczyk, Flemington, NJ (US); and Ravi Subramanyam, Belle Mead, NJ (US)
Assigned to Colgate-Palmolive Company, New York, NY (US)
Appl. No. 15/539,748
Filed by Colgate-Palmolive Company, New York, NY (US)
PCT Filed Dec. 26, 2014, PCT No. PCT/US2014/072423 § 371(c)(1), (2) Date Jun. 26, 2017, PCT Pub. No. WO2016/105432, PCT Pub. Date Jun. 30, 2016.
Prior Publication US 2017/0348207 A1, Dec. 7, 2017
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 8/27 (2006.01); A61K 6/20 (2020.01); A61K 6/74 (2020.01); A61K 8/24 (2006.01); A61K 33/42 (2006.01); A61Q 11/00 (2006.01)

CPC A61K 8/27 (2013.01) [A61K 6/20 (2020.01); A61K 6/74 (2020.01); A61K 8/24 (2013.01); A61K 33/42 (2013.01); A61Q 11/00 (2013.01); A61K 2800/58 (2013.01)]

3 Claims

1. An oral care composition, comprising:

a soluble zinc polyphosphate complex where the phosphorous to zinc mole ratio of the complex is 20:1, wherein the complex is made by combining zinc chloride and sodium hexametaphosphate and a solvent, wherein the solvent is water,

wherein the zinc chloride and the sodium hexametaphosphate are in sufficient amounts to provide a 20:1 mole ratio of phosphorus to zinc in the recited complex;

wherein when the soluble zinc polyphosphate complex is mixed with a protein a precipitate forms that can occlude dentinal tubules.