US 12,109,246 B2
Composition for the treatment and/or prevention of lower urinary tract symptoms
Sossio Morra, Monaco (MC)
Assigned to SÉRÉLYS PHARMA S.A.M., Monaco (MC)
Appl. No. 17/365,055
Filed by SERELYS PHARMA S.A.M., Monaco (MC)
PCT Filed Jan. 13, 2020, PCT No. PCT/EP2020/050671
§ 371(c)(1), (2) Date Jul. 1, 2021,
PCT Pub. No. WO2020/148224, PCT Pub. Date Jul. 23, 2020.
Claims priority of application No. 1900478 (FR), filed on Jan. 18, 2019.
Prior Publication US 2023/0149498 A1, May 18, 2023
Int. Cl. A61K 36/899 (2006.01); A61K 9/00 (2006.01); A61K 31/355 (2006.01); A61K 36/15 (2006.01); A61K 36/42 (2006.01); A61K 45/06 (2006.01); A61P 13/10 (2006.01)
CPC A61K 36/899 (2013.01) [A61K 9/0053 (2013.01); A61K 31/355 (2013.01); A61K 36/15 (2013.01); A61K 36/42 (2013.01); A61K 45/06 (2013.01); A61P 13/10 (2018.01); A61K 2236/331 (2013.01)] 15 Claims
 
1. A composition comprising:
a pollen extract consisting of an aqueous pollen extract obtained from a plant mixture belonging to the family Pinaceae and Poaceae, wherein the aqueous pollen extract is obtained from a mixture of:
45% to 90% aqueous extract of pollen of Secale cereale L. by weight of the total weight of the extract;
1% to 35% aqueous extract of pollen of Zea mays L. by weight of the total weight of the extract;
0.01% to 5% aqueous extract of pollen of Pinus sylvestris L. by weight of the total weight of the extract;
3% to 30% aqueous extract of pollen of Dactylis glomerata L. by weight of the total weight of the extract,
an aqueous extract of plant seeds belonging to the genus Cucurbita containing fatty acids at a content of less than 10% by weight of the total weight of the extract, vitamin E or its esters; and
an aqueous extract of the pistil of Zea mays L.,
wherein the composition treats lower urinary tract symptoms (LUTS) associated with the filling, micturition and/or post-micturition phases in women and, wherein the lower urinary tract symptoms (LUTS) associated with the filling, micturition and/or post-micturition phases in women is urinary incontinence.