US 12,109,182 B2
Administration of R-beta-hydroxybutyrate and related compounds in humans
Ryan Lowery, Tampa, FL (US); Jacob Wilson, Tampa, FL (US); and Terry LaCore, Melissa, TX (US)
Assigned to AXCESS GLOBAL SCIENCES, LLC, Salt Lake City, UT (US)
Filed by AXCESS GLOBAL SCIENCES, LLC, Salt Lake City, UT (US)
Filed on Jul. 2, 2021, as Appl. No. 17/367,206.
Application 17/367,206 is a continuation in part of application No. 15/491,924, filed on Apr. 19, 2017, granted, now 11,173,138.
Claims priority of provisional application 62/324,798, filed on Apr. 19, 2016.
Prior Publication US 2021/0393560 A1, Dec. 23, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/19 (2006.01); A61K 9/00 (2006.01); A61K 31/522 (2006.01); A61P 3/04 (2006.01); A61P 25/28 (2006.01)
CPC A61K 31/19 (2013.01) [A61K 9/0053 (2013.01); A61K 31/522 (2013.01); A61P 3/04 (2018.01); A61P 25/28 (2018.01)] 22 Claims
 
21. A composition for administering ketone bodies to a subject, comprising:
a non-racemic mixture of R-beta-hydroxybutyrate and S-beta-hydroxybutyrate,
wherein the non-racemic mixture contains from approximately 90% to less than 100% of R-beta-hydroxybutyrate and from greater than 0% to approximately 10% of S-beta-hydroxybutyrate,
wherein the R-beta-hydroxybutyrate comprises at least one salt of R-beta-hydroxybutyrate and R-beta-hydroxybutyric acid.