US 12,109,031 B2
System and method for local electrophysiological characterization of cardiac substrate using multi-electrode catheter
D. Curtis Deno, Andover, MN (US); and Ram K. Balachandran, Maple Grove, MN (US)
Assigned to St. Jude Medical, Cardiology Division, Inc., St. Paul, MN (US)
Filed by St. Jude Medical, Cardiology Division, Inc., St. Paul, MN (US)
Filed on Oct. 4, 2019, as Appl. No. 16/593,631.
Application 16/593,631 is a continuation of application No. 15/118,522, granted, now 10,470,682, previously published as PCT/US2015/017576, filed on Feb. 25, 2015.
Claims priority of provisional application 61/944,426, filed on Feb. 25, 2014.
Prior Publication US 2020/0253496 A1, Aug. 13, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 5/00 (2006.01); A61B 5/06 (2006.01); A61B 5/287 (2021.01); A61B 5/316 (2021.01); A61B 5/339 (2021.01); A61B 5/341 (2021.01); A61B 5/349 (2021.01); A61B 18/14 (2006.01); A61M 25/01 (2006.01); A61B 18/00 (2006.01)
CPC A61B 5/287 (2021.01) [A61B 5/062 (2013.01); A61B 5/068 (2013.01); A61B 5/316 (2021.01); A61B 5/339 (2021.01); A61B 5/341 (2021.01); A61B 5/349 (2021.01); A61B 5/6852 (2013.01); A61B 5/6858 (2013.01); A61B 18/1492 (2013.01); A61M 25/0127 (2013.01); A61B 5/0044 (2013.01); A61B 5/7239 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00839 (2013.01); A61B 2562/0214 (2013.01); A61B 2562/046 (2013.01); A61M 2025/0166 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A system for determining electrophysiological data comprising:
an electronic control unit configured to:
acquire electrophysiology signals from a plurality of electrodes of one or more catheters;
select at least one clique of electrodes from the plurality of electrodes to determine a plurality of local electric (E) field data points, wherein the at least one clique of electrodes comprises three electrodes;
process the electrophysiology signals from the at least one clique to derive the plurality of local E field data points associated with the at least one clique of electrodes, wherein each of the electrodes comprising the at least one clique of electrodes is associated with at least one of the plurality of local E field data points;
derive at least one orientation-independent bipolar electrophysiology signal from the plurality of local E field data points associated with the at least one clique of electrodes; and
output catheter-orientation-independent electrophysiologic information to a user or process.