US 11,783,914 B2
Method and system for panel characterizations
Zachary Apte, San Francisco, CA (US); Jessica Richman, San Francisco, CA (US); Daniel Almonacid, San Francisco, CA (US); Laurens Kraal, San Francisco, CA (US); Francisco Ossandon, San Francisco, CA (US); Juan Pablo Cardenas, San Francisco, CA (US); Elisabeth Bik, San Francisco, CA (US); and Audrey Goddard, San Francisco, CA (US)
Assigned to PSOMAGEN, INC., Rockville, MD (US)
Filed by PSOMAGEN, INC., Rockville, MD (US)
Filed on Sep. 18, 2017, as Appl. No. 15/707,907.
Application 15/707,907 is a continuation in part of application No. 15/606,743, filed on May 26, 2017, granted, now 10,803,991.
Application 15/606,743 is a continuation in part of application No. 14/919,614, filed on Oct. 21, 2015, granted, now 9,703,929, issued on Jul. 11, 2017.
Claims priority of provisional application 62/525,379, filed on Jun. 27, 2017.
Claims priority of provisional application 62/520,058, filed on Jun. 15, 2017.
Claims priority of provisional application 62/395,939, filed on Sep. 16, 2016.
Claims priority of provisional application 62/206,654, filed on Aug. 18, 2015.
Claims priority of provisional application 62/147,362, filed on Apr. 14, 2015.
Claims priority of provisional application 62/147,376, filed on Apr. 14, 2015.
Claims priority of provisional application 62/147,212, filed on Apr. 14, 2015.
Claims priority of provisional application 62/146,855, filed on Apr. 13, 2015.
Claims priority of provisional application 62/092,999, filed on Dec. 17, 2014.
Claims priority of provisional application 62/087,551, filed on Dec. 4, 2014.
Claims priority of provisional application 62/066,369, filed on Oct. 21, 2014.
Prior Publication US 2018/0137239 A1, May 17, 2018
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 33/48 (2006.01); G01N 33/50 (2006.01); G16B 30/10 (2019.01); G16H 20/60 (2018.01); G16B 30/00 (2019.01); G16B 40/00 (2019.01); G16H 10/40 (2018.01); G16H 50/20 (2018.01); G16B 20/00 (2019.01); G16B 40/20 (2019.01)
CPC G16B 30/10 (2019.02) [G16B 20/00 (2019.02); G16B 30/00 (2019.02); G16B 40/00 (2019.02); G16B 40/20 (2019.02); G16H 10/40 (2018.01); G16H 20/60 (2018.01); G16H 50/20 (2018.01); Y02A 90/10 (2018.01)] 9 Claims
 
1. A method for characterizing a panel of microorganism-related conditions associated with a set of taxa, the method comprising:
generating a taxonomic database comprising reference features associated with the set of taxa;
generating a microorganism sequence dataset for a user based on a biological sample collected from the user;
extracting a set of panel-associated features for the user based on the microorganism sequence dataset and by applying feature-selection rules;
determining a comparison between the reference features and the set of panel-associated features for the user;
determining a panel characterization for the user for the panel of microorganism-related conditions based on the comparison; and
promoting a therapy for a microorganism-related condition of the panel of microorganism-related conditions, based on the panel characterization,
collecting a diet-associated supplementary dataset associated with a dietary behavior of the user, wherein promoting the probiotic consumable comprises promoting the probiotic consumable to the user based on the diet-associated supplementary dataset and the panel characterization,
wherein extracting the set of panel-associated features by applying the feature selection rules comprises extracting microbiome composition diversity features and microbiome functional diversity features of the set of panel-associated features based on the microorganism sequence dataset, and wherein determining the comparison comprises determining the comparison of the reference features with the microbiome composition diversity features and the microbiome functional diversity features,
wherein promoting the therapy comprises promoting a probiotics-related therapy for the microorganism-related condition, wherein the probiotics-related therapy is associated with the set of taxa, and wherein the set of taxa comprises at least one of: Bacillus coagulans (species), Bifidobacterium animalis (species), Clostridium butyricum (species), Lactobacillus brevis (species), Lactobacillus coryniformis (species), Lactobacillus fermentum (species), Lactobacillus helveticus (species), Lactobacillus rhamnosus (species), and Streptococcus salivarius (species).